Results 161 to 170 of about 1,706,547 (267)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Seasonal changes in 3D space use and foraging strategies in the avivorous bat <i>Ia io</i>. [PDF]

Zool Res
Wang ZQ, Gong LX, Si M, Huang ZL, Wu H, Feng J, Jiang TL.   +6 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Wild pigs impact reproductive season movements and space use of wild turkeys. [PDF]

Mov Ecol
Stoakley TE, Zenas SJ, Brown VR, Smith MD, Gulsby WD, Collier BA, Ditchkoff SS.   +6 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Impact of artificial feeding policies on space use and competition dynamics in overwintering hooded crane and goose populations. [PDF]

PLoS One
Son JJ, Lee JH, Ha JM, Kang NR, Hwang SM, Jang JU, Cho DH, Kim SY, Choi WS, Shin YU, Sung HC.   +10 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

The influence of human presence and footprint on animal space use in US national parks. [PDF]

Proc Biol Sci
Gaynor KM, Hayes FP, Manlove K, Galloway N, Benson JF, Cherry MJ, Epps CW, Fletcher RJ, Orrock J, Smith JA, Aiello C, Belant JL, Berger J, Biel M, Bright J, Bump J, Burchett M, Butler C, Carlson J, Cole EK, Darby N, Degutis E, Dewey S, Figura P, Gable TD, Gagnon J, Glass DM, Green JR, Gunther K, Haroldson MA, Hersey KR, Holton BP, Homkes AT, Hoy SR, Hughson D, Joly K, Leahy R, Lee-Roney C, Lester R, MacNulty D, Magnuson M, Martin D, Mazur R, Moore S, Orning EK, Patrick K, Peterson RO, Potvin L, Prentice PR, Riley SPD, Romanski MC, Roug A, Sikich JA, Simpson N, Sloan W, Smith DW, Sorum M, Sprague S, Stahler D, Stephenson J, Stephenson TR, Stroud-Settles J, van Manen FT, Vucetich JA, Wilmot K, Windels S, Wolf TM, Cross PC.   +67 more
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Comparative Space Use of Sympatric Sharks at a Remote Island in the South Pacific Ocean. [PDF]

Ecol Evol
Matley JK, Roberts CN, Clarke TM, Meyer L, Doane MP, Dinsdale EA, Scott M, Barnett A, Huveneers C.   +8 more
europepmc   +1 more source