Results 31 to 40 of about 4,749,326 (300)

What can functional transcranial Doppler ultrasonography reveal about the cerebral lateralization of writing

FEBS Letters, EarlyView.
Which brain hemisphere controls writing? This review synthesizes all five functional transcranial Doppler studies of writing (handwriting and typing) published to date in adults and children. Right‐handers show left‐hemispheric dominance for the linguistic component of writing (written word generation), whereas findings for left‐handers remain ...
Marietta Papadatou‐Pastou
wiley   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

FEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim, Thi Thanh Mai Tran, Nakyung Kang, Min‐Woo Lee, Mihye Lee   +4 more
wiley   +1 more source

Dayside aurora and the role of IMF ∣B_y∣/∣B_z∣: detailed morphology and response to magnetopause reconnection [PDF]

Annales Geophysicae, 2004
We document the detailed spatio-temporal structure of the dayside aurora during intervals of ongoing dayside magnetopause reconnection, primarily during interplanetary magnetic field (IMF) Bz≤0 conditions.
P. E. Sandholt, C. J. Farrugia, W. F. Denig   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Active Flutter Suppression of a Wing Section in the Subsonic, Sonic and Supersonic Regimes by the H_∞ Control Method

Aerospace
This paper compares various procedures for determining the optimal control law for a wing section in compressible flow. The flow regime includes subsonic, sonic and supersonic flows.
Álvaro Muñoz, Pablo García-Fogeda
doaj   +1 more source

Preloaded Structures for Space Exploration Vehicles [PDF]

, 2018
This paper is devoted to the design and simulation of a rover equipped with 4 preloaded structure legs. Space exploration vehicles (rovers) are employed for moving sensors, transporting planet samples and manipulating small modules. In order to perform such tasks with high accuracy, high mechanical stiffness frames are required.
Seriani, S., Scalera, L., Gasparetto, A., Gallina, P.   +3 more
openaire   +3 more sources

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Unified OSTBC-based communication scheme for cooperative space vehicles

The Journal of Engineering, 2019
In many spatial cooperative vehicle networks, omni-directional communication is preferred due to its flexibility for networking. In the recent studies, space time code was shown to be an effective approach for improving the performance of the omni ...
Jian Geng, Hongyan Liu, Wen Jin, Xinfeng Yan, Jin Xu   +4 more
doaj   +1 more source

Detailed dayside auroral morphology as a function of local time for southeast IMF orientation: implications for solar wind-magnetosphere coupling [PDF]

Annales Geophysicae, 2004
In two case studies we elaborate on spatial and temporal structures of the dayside aurora within 08:00-16:00 magnetic local time (MLT) and discuss the relationship of this structure to solar wind-magnetosphere interconnection topology and the ...
P. E. Sandholt, C. J. Farrugia, W. F. Denig   +2 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source