Results 31 to 40 of about 40,337 (302)
Spaceflight modulates gene expression in the whole blood of astronauts [PDF]
, 2016 Astronauts are exposed to a unique combination of stressors during spaceflight, which leads to alterations in their physiology and potentially increases their susceptibility to disease, including infectious diseases.
Barrila, Jennifer +7 more
core +2 more sources
Skeletal Responses to Spaceflight [PDF]
Advances in Space Biology and Medicine, 1991 The role of gravity in the determination of bone structure is elucidated by observations in adult humans and juvenile animals during spaceflight. The primary response of bone tissue to microgravity is at the interface of the mineral and matrix in the process of biomineralization.
SaraBond Arnaud, Emily Morey-Holton
openaire +3 more sources
Scientific Reports, 2021 Spaceflight induces hepatic damage, partially owing to oxidative stress caused by the space environment such as microgravity and space radiation. We examined the roles of anti-oxidative sulfur-containing compounds on hepatic damage after spaceflight.
Ryo Kurosawa +7 more
doaj +1 more source
Nrf2 alleviates spaceflight-induced immunosuppression and thrombotic microangiopathy in mice
Communications Biology, 2023 Spaceflight-related stresses impact health via various body systems, including the haematopoietic and immune systems, with effects ranging from moderate alterations of homoeostasis to serious illness.
Ritsuko Shimizu +15 more
doaj +1 more source
Hierarchical Reinforcement Learning Framework for Stochastic Spaceflight Campaign Design [PDF]
Journal of Spacecraft and Rockets (Articles in Advance), 2022, 2021 This paper develops a hierarchical reinforcement learning architecture for multimission spaceflight campaign design under uncertainty, including vehicle design, infrastructure deployment planning, and space transportation scheduling. This problem involves a high-dimensional design space and is challenging especially with uncertainty present.
arxiv +1 more source
Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function. [PDF]
, 2019 With extended stays aboard the International Space Station (ISS) becoming commonplace, there is a need to better understand the effects of microgravity on cardiac function. We utilized human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)
Agrawal +30 more
core +1 more source
The effectiveness of RNAi in Caenorhabditis elegans is maintained during spaceflight. [PDF]
PLoS ONE, 2011 Overcoming spaceflight-induced (patho)physiologic adaptations is a major challenge preventing long-term deep space exploration. RNA interference (RNAi) has emerged as a promising therapeutic for combating diseases on Earth; however the efficacy of RNAi ...
Timothy Etheridge +10 more
doaj +1 more source
Frontiers in Astronomy and Space Sciences, 2023 The field of space physics has a long history of utilizing dimensionality reduction methods to distill data, including but not limited to spherical harmonics, the Fourier Transform, and the wavelet transform.
D. da Silva +8 more
doaj +1 more source
Towards an integrated scientific and social case for human space exploration [PDF]
, 2004 I will argue that an ambitious programme of human space exploration, involving a return to the Moon, and eventually human missions to Mars, will add greatly to human knowledge. Gathering such knowledge is the primary aim of science, but science's compart-
Crawford, Ian
core +1 more source
A statistical method (cross-validation) for bone loss region detection after spaceflight. [PDF]
, 2010 Astronauts experience bone loss after the long spaceflight missions. Identifying specific regions that undergo the greatest losses (e.g. the proximal femur) could reveal information about the processes of bone loss in disuse and disease.
Chu, Philip W +7 more
core +3 more sources