Results 31 to 40 of about 7,041 (240)

From the Discovery of the Giant Magnetocaloric Effect to the Development of High‐Power‐Density Systems

Advanced Materials Technologies, EarlyView.
The article overviews past and current efforts on caloric materials and systems, highlighting the contributions of Ames National Laboratory to the field. Solid‐state caloric heat pumping is an innovative method that can be implemented in a wide range of cooling and heating applications.
Agata Czernuszewicz, Yaroslav Mudryk, Jun Cui, Lucas Griffith, Duane D. Johnson, Julie Slaughter   +5 more
wiley   +1 more source

A Cryopreservation‐Based Supply Chain Strategy for Extrusion Bioprinting in Space

Advanced Materials Technologies, EarlyView.
Extrusion bioprinting on crewed space platforms requires a bioink that stays functional along the logistic chain. Here, cells and biomaterial ink travel separately, the cells cryopreserved and the ink cold stored, and are combined only minutes before printing.
Johannes Windisch, Max von Witzleben, Richard Frank Richter, Finn Dani, Constantin Greil, Sarah Duin, Anja Lode, Michael Gelinsky   +7 more
wiley   +1 more source

Impacts of the Spaceflight to the Immune System

Hanggong uju uihakoeji, 2021
Changes the gravity has a significant affect on the immune system. Astronauts experience the gravity changing during spaceflight, especially when launching and landing they experience hypergravity, and during spaceflight they feel microgravity.
Doston Sultonov, Young Hyo Kim
doaj   +1 more source

Kaempferol Attenuates Spaceflight‐Associated Knee Cartilage Degradation by Targeting NOX4‐Mediated Mitochondrial Dysfunction

Advanced Science, EarlyView.
We have shown that both simulated and actual spaceflight contribute to cartilage degradation in the knees of mice. Using RNA sequencing and bioenergetic profiling, we identified NADPH oxidase 4 (NOX4) as a key factor driving these changes. Additionally, we found that kaempferol, a naturally occurring flavonoid that binds directly to NOX4, reduces ...
Yuesong Yin, Ruiling Xu, Meagan J. Makarczyk, Jia‐Jun Liu, Silvia Liu, Matthew Z. Shi, Roberta Di Carlo, Michael F. Almeida, Alex Garris, Sarah Day, Rebekah Sanchez‐Hodge, Jonathan C. Schisler, Aleeza H. Zilberman, Noah G. Allen, Angela J. Kubik, Elizabeth A. Blaber, Arnold Z. Olali, Wanqing Xie, Douglas C. Wallace, Christopher E. Mason, Peter G. Alexander, Giuseppe Intini, Afshin Beheshti, Hang Lin   +23 more
wiley   +1 more source

Spaceflight enhances cell aggregation and random budding in Candida albicans. [PDF]

PLoS ONE, 2013
This study presents the first global transcriptional profiling and phenotypic characterization of the major human opportunistic fungal pathogen, Candida albicans, grown in spaceflight conditions. Microarray analysis revealed that C. albicans subjected to
Aurélie Crabbé, Sheila M Nielsen-Preiss, Christine M Woolley, Jennifer Barrila, Kent Buchanan, James McCracken, Diane O Inglis, Stephen C Searles, Mayra A Nelman-Gonzalez, C Mark Ott, James W Wilson, Duane L Pierson, Heidemarie M Stefanyshyn-Piper, Linda E Hyman, Cheryl A Nickerson   +14 more
doaj   +1 more source

Text-to-image artificial intelligence to understand astronaut visual phenomena during spaceflight

The Pan-American Journal of Ophthalmology, 2023
Astronauts have documented visual phenomena during spaceflight. However, given that these are only experienced by the astronaut themselves, these unique neuro-ophthalmic visual phenomena occur while in space which remain poorly understood by ...
Ethan Waisberg, Joshua Ong, Mouayad Masalkhi, Nasif Zaman, Andrew G Lee, Alireza Tavakkoli   +5 more
doaj   +1 more source

Fun‐sized library prep: Miniaturization is a valid method for per‐sample cost reduction in targeted sequencing of angiosperm DNA

Applications in Plant Sciences, EarlyView.
Abstract Premise Genomic analysis of population structure is important for understanding plant genetic diversity among and within populations. A limitation to the broader application of genetics in conservation and related fields is the cost of obtaining large datasets.
Madison R. Bullock, Mohamed Fokar, Rylee D. Creek, Eliot A. Stevens, Matthew G. Johnson   +4 more
wiley   +1 more source

Mechanism study of an articular cartilage repair material and its forward‐looking test for space medicine

BMEMat, EarlyView.
The regeneration process following dLhCG engraftment progressed through four distinct and interconnected stages. dLhCG maintained its regenerative efficacy after 6 months of cosmic exposure, supporting its potential application in space medicine.
Xu Hu, Hang Yao, Zhen Zhang, Zhonglian Wu, Huiqun Zhou, Bangheng Liu, Liang Ma, Yulei Mu, Dong‐An Wang   +8 more
wiley   +1 more source

Post‐Processing Probabilistic Forecasts of the Solar Wind by Data Mining Similar Scenarios

Space Weather
The solar wind speed at Earth is one of the most important parameters regarding the effects of space weather on society. Thus far, most approaches for predicting the solar wind speed produce a single‐value time series without uncertainty, or utilize ...
Daniel E. daSilva, Yash Parlikar, Shaela I. Jones, Charles N. Arge   +3 more
doaj   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source