Results 171 to 180 of about 233,779 (288)

Achieving High Spatial Resolution Transmission Electron Microscopy Studies in Closed Liquid Cells

Advanced Materials, EarlyView.
Achieving high spatial resolution is important for resolving nanoscale dynamic processes and structural transformations in liquid environments, yet remains challenging in liquid cell transmission electron microscopy (LCTEM). This review highlights key strategies, including mitigating membrane bulging, displacing or redistributing local liquid ...
Siqi Guo, Hongyu Sun, Le Shu, Xuejin Ge, Raquel Aymerich‐Armengol, Siyuan Zhang, Long Ren, Ningyan Cheng, Christina Scheu, Binghui Ge   +9 more
wiley   +1 more source

Comparative characterization of Cas12f orthologs reveals mechanistic features underlying enhanced genome editing efficiency. [PDF]

Nat Struct Mol Biol
Guan K, Ocampo RF, Matheus Carnevali PB, Castelle CJ, Gonzalez-Osorio L, Castanzo DT, Thomas NC, Brothers M, Dangerfield TL, Hooper MM, West MS, Appleby NM, Krudop I, Lamothe RC, Aliaga Goltsman DS, Alexander LM, Butterfield CN, Johnson KA, Brown CT, Taylor DW.   +19 more
europepmc   +1 more source

Inverse Design of Nanoparticulate Materials

Advanced Materials, EarlyView.
Inverse design shifts nanomaterial development from empirical trial‐and‐error to predictive model‐driven strategies. It can rely on knowledge‐based, data‐based, or hybrid process and property functions. This perspective article provides a practical framework for applying inverse design based on instructive examples. It discusses which modeling approach
Nabi Etienne Traoré, Annika Mauch, Michelle Berthold, Lukas Pflug, Wolfgang Peukert, Nicolas Vogel   +5 more
wiley   +1 more source

Structure of the 30S translation initiation complex coupled to paused RNA polymerase and its potential for riboregulation. [PDF]

Nat Commun
Roske JJ, Paris G, Goyal A, Rodnina M, Zenkin N, Bandyra KJ, Luisi BF.   +6 more
europepmc   +1 more source

Microgels Enable iPSCs to Assemble, Expand, and Differentiate Into Organoids—From Sizable to High‐Throughput

Advanced Materials, EarlyView.
A chemically defined PEG‐based microgel platform enables scalable, reproducible production of three‐dimensional microgel‐iPSC constructs in multiple sizes. The system is compatible with high‐throughput automation and supports human iPSC expansion and differentiation within a single construct, including directed differentiation into cardiac organoids ...
Laura Klasen, Matthias Mork, Ramin Nasehi, Vasudha Turuvekere Krishnamurthy, Kira Zeevaert, Aaron Babendreyer, Jacopo Di Russo, Wolfgang Wagner, Laura De Laporte   +8 more
wiley   +1 more source

Structures of EHD2 filaments on curved membranes provide a model for caveolar neck stabilization. [PDF]

Nat Commun
Vázquez-Sarandeses E, Mikirtumov V, Noel JK, Kudryashev M, Daumke O.   +4 more
europepmc   +1 more source

Soft and Transient Bioelectronics Enabled by Polymer‐Free Ti3C2Tx MXene Hydrogels

Advanced Materials, EarlyView.
We present Ti3C2Tx MXene hydrogel (MXgel) bioelectronics, a soft, flexible, and fully transient platform for high‐fidelity neural recording and stimulation. MXgel bioelectronics exhibit exceptional electrical conductivities, low electrochemical impedances, and high charge injection capacities.
Raghav Garg, Franco A. Laimo, Stefano Ippolito, Prastuti Upadhyay, Spencer R. Averbeck, Dimitris Boufidis, Charles‐Antoine Assenmacher, Dayo O. Adewole, Sai Panigrahy, Bita Soltan Mohammadlou, Lucy Plant, Yuan Zhang, Andrew G. Richardson, Yury Gogotsi, D. Kacy Cullen, Flavia Vitale   +15 more
wiley   +1 more source

Structural insights into RNA phosphorylation by the RNase PNK module of the human rixosome complex. [PDF]

Nucleic Acids Res
Gordon J, Seely SM, Wang H, Krahn JM, Peele WA, Borgnia MJ, Warren AJ, Stanley RE.   +7 more
europepmc   +1 more source

Fabrication of Aligned Polycaprolactone Nanofibrillar Bundles to Control Cell‐Mediated Collagen Deposition in Engineered Cartilage

Advanced Materials, EarlyView.
Melt electrofibrillation (MEF) enables the fabrication of nanofibrillar PCL scaffolds with defined architectures that guide cellular alignment and retention during cartilage tissue engineering. Unlike conventional melt electrowriting, MEF consistently directs collagen type II‐rich extracellular matrix organization, providing a tunable platform to ...
Alba Pueyo Moliner, Lennard Spauwen, James L. Martin Robinson, Ángela García Grech, Isabelle Martinier, Sara Grasselli, Aylin Kara Özenler, Matthias Ryma, Jürgen Groll, Mylène de Ruijter, Jos Malda   +10 more
wiley   +1 more source

Liquid Surface Synthesis of Ultrathin Two-Dimensional Metal Halide Perovskite. [PDF]

ACS Mater Lett
Li J, Kot M, Cielica N, Pinna J, Chen L, Modena F, Lutsen L, Van Gompel WTM, Loi MA.   +8 more
europepmc   +1 more source