Results 41 to 50 of about 233,779 (288)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Nonlinear vibrations of a 3 × 3 reduced scale PWR fuel assembly supported by spacer grids

, 2020
The core of Pressurized Water Reactors (PWR) is composed by nuclear fuel assemblies, bundles of slender fuel rods containing uranium pellets, kept in position by spacer grids equipped with elastic elements for retention, and exposed to an axial flow of ...
Faedo L., Ferrari G., Karazis K., Amabili M., Balasubramanian P., Le Guisquet S., Franchini G., Giovanniello F.   +7 more
core   +1 more source

Numerical evaluation of hybrid spacer grid integrating mixing channel with mixing vane for small modular reactors

Nuclear Engineering and Technology
Spacer grids in light-water reactor fuel assemblies must balance heat-transfer augmentation via subchannel mixing against the pressure-loss penalty. This trade-off is especially consequential in natural-circulation small modular reactors (SMRs), where ...
Hyeon Ji Kim, Doyeong Lim, In Cheol Bang
doaj   +1 more source

Numerical investigation of turbulent mixed convection flow and heat transfer characteristics of 2 × 2 subchannels with spacer grids

Energy Science & Engineering, 2023
In turbulent mixed convection conditions, flow and heat transfer can deteriorate under specific conditions, thus affecting the performance of the safety of the system, which could imperil the safety of the nuclear reactor. In this paper, by analyzing the
Jianping Long, Bao‐Wen Yang, Ting Wu, Bin Zhang   +3 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Estimation of Dynamic Stiffness and Analysis of Error Source of Spacer Grid for Pressurized Water Reactor Fuel Assembly

Yuanzineng kexue jishu
Fuel assemblies are core components in pressurized water reactor (PWR), in which spacer grids serve as essential structural elements to support fuel rods, maintain fuel rod spacing, mix coolant, and resist external loads.
ZHOU Ding1, 2, HUANG Congcai2, LI Tianyong2, QIAO Hongwei2, CUI Yihang2, ZHAO Xiangji2, MA Jianzhong2, SUN Lei2
doaj   +1 more source

An insulating grid spacer for large-area MICROMEGAS chambers [PDF]

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2002
We present an original design for large area gaseous detectors based on the MICROMEGAS technology. This technology incorporates an insulating grid, sandwiched between the micro-mesh and the anode-pad plane, which provides an uniform 200 $μ$m amplification gap.
Bernard, D., Delagrange, H., d'Enterria, D.G., Guay, M. Le, Martinez Garcia, Gines, Mora, M.J., Pichot, P., Roy, Daniel, Schutz, Y., Gandi, A., de Oliveira, R.   +10 more
openaire   +4 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Small molecule tandem organic photovoltaic cells incorporating an α-NPD optical spacer layer [PDF]

, 2013
We report an improvement in power conversion efficiency in a small molecule tandem organic photovoltaic (OPV) device by the optimisation of current balancing of the sub-cells using an optical spacer layer. A co-deposited layer of N,N’-bis(1-naphthyl)-N,N′
Howells, Thomas J., Jones, T. S. (Tim S.), New, Edward G., Sullivan, Paul J.   +3 more
core   +1 more source