Results 151 to 160 of about 1,630,376 (260)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Octopus7 : don't show me your poetry

open access: yes, 2007
Catalogue of an exhibition held at Gertrude Contemporary Art Spaces, Fitzroy, Victoria, 3 August - 1 September, 2007.Guest curator: Robert Cook.Artists: Alin Huma, Amanda Maxwell, Geoff Newton, Josh Petherick, Paul Knight, Is Not ...
Gertrude Contemporary Art Spaces
core  

Testing for Genetic Interactions in Complex Disease With Distance Correlation. [PDF]

open access: yesBiom J
Castro-Prado F   +4 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Octopus 6 : we know who we are.

open access: yes, 2006
Guest curator and catalogue essay, Zara Stanhope.;Exhibition held at Gertrude Contemporary Art Spaces, 7 July-19 August 2006.;Artists exhibited Zehra Ahmed, Matthew Hunt, Helen Johnson, Ash Keating, Merran Sierakowski and Bernie Slater.Bibliography: p ...
Gertrude Contemporary Art Spaces
core  

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