Results 121 to 130 of about 4,661,060 (392)

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

open access: yesArthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti   +19 more
wiley   +1 more source

The Public Image of Soviet Science During Franco’s Spain

open access: yesHoST
During the second half of the 1950s, Spain received economic and technological assistance from the Western bloc, which encouraged a transformation of the country’s socioeconomic structures.
Ruiz-Castell Pedro
doaj   +1 more source

Spain and NATO: financial dimension

open access: yesИбероамериканские тетради, 2019
The paper deals with the degree of Spanish involvement in NATO, the financial dimension of this problem is being assessed. The article analyzes the consequences of the increase in defense expenditures.
N. A. Rostov
doaj   +1 more source

Response to allopurinol and febuxostat according to the fractional excretion of urate in men with gout

open access: yesArthritis Care &Research, Accepted Article.
Background Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of urate (FEUA) also modulates this response and relates to oxypurinol concentrations. We further evaluated its potential influence
Pascal Richette   +13 more
wiley   +1 more source

Spain and Don Ernesto. History of mutual love

open access: yesИбероамериканские тетради, 2019
Bullfighting and wars, sun and waves, inevitable danger and careless rest make an inconsistent picture of Spain, which appears before us due to Ernest Hemingway’s labour. He was fond of this country, we shall try to understand, what for?
A. Sudakova
doaj   +1 more source

The geography fieldwork experience: Spain 2008 [PDF]

open access: yes, 2008
In the last week of April, Dr Tony Mellor and five colleagues from the School of Applied Sciences took 34 Geography students on field work to Andalucia in southern Spain.
Mellor, Antony
core  

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients with Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

open access: yesArthritis Care &Research, Accepted Article.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; NCT04179032) used three‐weight‐band ...
Hermine I. Brunner   +14 more
wiley   +1 more source

Spain’s party system development trends in the context of the electoral cycle 2019

open access: yesИбероамериканские тетради, 2019
The topicality of the article is that the party system of Spain is undergoing serious transformations, the positioning of political forces and their ideologies, the organizational structure are changing significantly. National parliamentary elections are
A. Baranov
doaj   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

open access: yesAdvanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers   +10 more
wiley   +1 more source

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