Results 31 to 40 of about 323,483 (259)

Physicochemical properties and release behavior of Span 60/Tween 60 niosomes as vehicle for α-Tocopherol delivery

LWT, 2017
Abstract In this study, Niosomes, as vehicles for α-Tocopherol were formulated applying film hydration method to improve the availability and stability of α-Toc. Parameters affecting encapsulation efficiency (EE), mean size, polydispersity index and zeta potential were investigated, along with the different molar ratio of Span 60/Tween 60, presence ...
Ladan Basiri, Ghadir Rajabzadeh, Aram Bostan   +2 more
openaire   +1 more source

Gene copy number variation spanning 60 million years of human and primate evolution [PDF]

Genome Research, 2007
Given the evolutionary importance of gene duplication to the emergence of species-specific traits, we have extended the application of cDNA array-based comparative genomic hybridization (aCGH) to survey gene duplications and losses genome-wide across 10 primate species, including human. Using human cDNA arrays that contained 41,126 cDNAs, corresponding
Laura, Dumas, Young H, Kim, Anis, Karimpour-Fard, Michael, Cox, Janet, Hopkins, Jonathan R, Pollack, James M, Sikela   +6 more
openaire   +2 more sources

Développement d’un collutoire à base d’huile essentielle de Cymbopogon giganteus Chiov. (Poaceae) destinée à être utilisée dans le traitement des angines de gorge

Journal Africain de Technologie Pharmaceutique et Biopharmacie
Sur la base d’études antérieures, ayant démontré une efficacité in vitro de l’huile essentielle de Cymbopogon giganteus Chiov. (Poaceae) sur les germes impliqués dans l’angine de gorge, l’objectif de cette étude était de développer un collutoire à base ...
Habib, Dr ASSANHOU Gabin Dr ASSANHOU Gabin, Farouk Saroukou, Agoin Gérard Dossou, Parfait Doffon, Engelbert Agbokponto, Achille Yemoa, Fernand Gbaguidi   +7 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Formulation of Risperidone Nano Niosomal Vesicular System by Ecofriendly Direct Ultrasonication Method

Iraqi Journal of Pharmaceutical Sciences
Risperidone is atypical antipsychotic agent used mainly in treating schizophrenia, it is classified as class II in BCS classification. Nanovesicular system may provide a circumvent to these hurdles.
Mohamed I. Al- Shadedi, Fatima J. Al_Gawhari   +1 more
doaj   +1 more source

A series of five population-specific Indian brain templates and atlases spanning ages 6 to 60 years [PDF]

Human Brain Mapping, 2020
Abstract Anatomical brain templates are commonly used as references in neurological MRI studies, for bringing data into a common space for group-level statistics and coordinate reporting. Given the inherent variability in brain morphology across age and geography, it is important to have templates that are as ...
Bharath Holla, Paul A. Taylor, Daniel R. Glen, John A. Lee, Nilakshi Vaidya, Urvakhsh Meherwan Mehta, Ganesan Venkatasubramanian, Pramod Kumar Pal, Jitender Saini, Naren P. Rao, Chirag K. Ahuja, Rebecca Kuriyan, Murali Krishna, Debashish Basu, Kartik Kalyanram, Amit Chakrabarti, Dimitri Papadopoulos Orfanos, Gareth J. Barker, Robert W. Cox, Gunter Schumann, Rose Dawn Bharath, Vivek Benegal   +21 more
openaire   +3 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source