A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento +3 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak +4 more
wiley +1 more source
Oil-in-water emulsion technique enhancement for viscous crude oil flow in pipelines [PDF]
, 2015 The production of heavy crude oil is limited due to its high viscosity. It is expected to increase in the future as low viscosity crudes are depleted. The high viscosity lead to the increasing of pump energy as it creates high pressure drop.
Muhammad Fawwaz, Abdul Wahab
core
Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket +14 more
wiley +1 more source
Preparation of morphology-controllable PGMA-DVB microspheres by introducing Span 80 into seed emulsion polymerization. [PDF]
RSC Adv, 2018 Cong H +6 more
europepmc +1 more source
Arthritis Care &Research, EarlyView.Objective Systemic lupus erythematosus (SLE) is a heterogenous inflammatory condition with widely varying global prevalence estimates. The frequency of SLE in the general population of Australia has been reported to be notably lower than contemporary estimates in countries such as the United States or United Kingdom, at 19 to 39 per 100,000 as opposed ...
Lucinda Roper +7 more
wiley +1 more source
Phenol recovery and removal from aqueous solutions by emulsion liquid membranes
MANAS: Journal of Engineering, 2019 Emulsiontype liquid membrane process is a new and effective method for separation ofmixtures with applications in the nuclear industry, hydrometallurgy andwastewater treatment.
Durdu Topkara +3 more
doaj
Optimization of process parameters in preparation of tocotrienol-rich red palm oil-based nanoemulsion stabilized by Tween80-Span 80 using response surface methodology. [PDF]
PLoS One, 2018 Chong WT +6 more
europepmc +1 more source
Flutter Investigation of 60 Degree to 80 Degree Delta-Planform Surfaces at a Mach Number of 7.0 [PDF]
The flutter characteristics of a series of half-span delta surfaces which had leading-edge sweep angles ranging from 60 degrees to 80 degrees were investigated in helium flaw at a Mach number of 7.0 in the Langley hypersonic aeroelasticity tunnel.
Hannah, M. E., Miller, R. W.
core +1 more source
Arthritis Care &Research, Accepted Article.Introduction Rheumatic and musculoskeletal diseases(RMDs) are leading causes of physical disability, necessitating support with activities of daily living(ADLs). This study describes social care received by patients with RMDs in two disperate regions of England: Salford(urban) and Norfolk(rural).
Mehreen Somro +6 more
wiley +1 more source