Results 231 to 240 of about 891,805 (317)

Exploring the double deficit hypothesis in Spanish schoolchildren using latent profile analysis

open access: yesJournal of Research in Reading, Volume 49, Issue 1, February 2026.
Abstract Background Dyslexia is a neurodevelopmental disorder caused by deficits in phonological awareness (PA). According to the Double Deficit Hypothesis (DDH), Rapid Automatic Naming (RAN) deficit is another potential independent cause. However, the evidence from studies with languages that vary in orthographic consistency is mixed.
Amanda Flores   +3 more
wiley   +1 more source

Astrocyte Senescence Impairs Synaptogenesis due to Thrombospondin‐1 Loss

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Senescent hippocampal astrocytes lose TSP secretion, impairing excitatory synaptogenesis via the α2δ‐1 pathway. Restoring TSP‐1 rescues synaptic formation, revealing the contribution of astrocyte senescence to age‐related hippocampal synaptic decline.
Stefano Ercoli   +3 more
wiley   +1 more source

Optochemical modulation of corneal cold nerve terminal impulse activity with a photochromic ion channel blocker

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 3, Page 545-559, February 2026.
Background and Purpose The functional organization of corneal cold nerve endings, critical structures in maintaining the ocular surface, remains poorly understood. Here, the photoisomerizable small‐molecule diethylamine‐azobenzene‐quaternary ammonium (DENAQ) was used to photomodulate activity of cold‐sensing nerve terminals in control and chronic tear ...
David Ares‐Suárez   +11 more
wiley   +1 more source

Vulnerability of marine megafauna to global at‐sea anthropogenic threats

open access: yesConservation Biology, Volume 40, Issue 1, February 2026.
Abstract Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened ...
Michelle VanCompernolle   +309 more
wiley   +1 more source

Scarring and Selection in the Great Irish Famine

open access: yesThe Economic History Review, Volume 79, Issue 1, Page 189-220, February 2026.
Abstract How do famines shape the health of survivors? We examine the long‐term impact of the Great Irish Famine (1845–52) on human stature, distinguishing between adverse scarring effects and the apparent resilience of survivors due to selection. Using anthropometric data from more than 14500 individuals born before, during, and after this famine, we ...
Matthias Blum   +2 more
wiley   +1 more source

Vaccination Recommendations in Patients With Atopic Dermatitis Treated With JAK Inhibitors

open access: yesInternational Journal of Dermatology, Volume 65, Issue 2, Page 230-237, February 2026.
Inmunization and Screening Protocol for the Safe Initiation of JAK Inhibitors. ABSTRACT Atopic dermatitis therapy has undergone a revolutionary change with the introduction of Janus kinase (JAK) inhibitors. Despite their general safety profile, these immunomodulatory drugs require special precautions with respect to infection risk and vaccine ...
Mariano Ara‐Martín   +5 more
wiley   +1 more source

Differential peritoneal resident macrophage depletion and omental milky spot disruption after high versus low clodronate‐loaded liposome dose treatment

open access: yesImmunology &Cell Biology, Volume 104, Issue 2, Page 139-149, February 2026.
In this study, we found that intraperitoneal injection of a high (standard) clodronate‐loaded liposome dose induced persistent peritoneal macrophage depletion, paralleled by marked inflammation and compromised omental integrity. Conversely, low liposome dose caused transient macrophage depletion, low inflammation and no omental alterations, ensuring ...
Margarita Ferriz   +5 more
wiley   +1 more source

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