Results 241 to 250 of about 891,805 (317)
We utilised long‐read Nanopore sequencing to characterise the transcriptome of ferret cell lines stimulated with IFN‐α as well as nasal turbinates from ferrets infected with influenza A virus. We identified novel genes and isoforms and observed elongation of poly(A) tails in the ribosome and Coronavirus Disease‐19 pathways in response to IFN‐α ...
Rubaiyea Farrukee +7 more
wiley +1 more source
On the Centenary of the Spanish Flu: Being Prepared for the Next Pandemic. [PDF]
Liu WJ, Bi Y, Wang D, Gao GF.
europepmc +1 more source
Challenge Specific Modulation of Responses to Adjuvant‐Induced Innate Immune Memory
We utilised a commercially available adjuvant formulation to study the induction, maintenance, and consequences of innate immune memory. Using functional assays on bone marrow‐derived innate cells, extensive transcriptomic analysis of haematopoietic progenitors, and challenge models of spirochetal infection, nonspecific inflammation, and model antigen ...
Samuel T. Pasco +24 more
wiley +1 more source
Change in healthcare utilization before and after COVID‐19 using data from 1.5 million individuals
Abstract Background and objective Post‐infectious sequelae can increase burden on healthcare systems. We aimed to assess the long‐term effect of COVID‐19 on healthcare utilization across all levels of care. Methods In this register‐based cohort study, we included all adult (≥18 years) residents in Sweden's two largest counties with a registered COVID ...
Maria Bygdell +13 more
wiley +1 more source
The Redox Properties of Polyphenols and Their Role in ROS Generation for Biomedical Applications
The dual redox nature of polyphenols enables antioxidant activity and controlled reactive oxygen species (ROS) generation. This review details the biomedical applications of polyphenols in materials such as nanoparticles, coatings, and hydrogels for antimicrobial, tissue regeneration, and cancer therapies.
Jose Bolaños‐Cardet +7 more
wiley +2 more sources
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease (MND) characterized by progressive degeneration of both upper and lower motor neurons, along with skeletal muscles innervated by them. The identification of key molecules involved in disease pathology remains crucial for ALS, as no curative treatment is currently available ...
Paloma Martínez‐Alesón +3 more
wiley +1 more source
100 years on: the Spanish Flu, pandemics and keeping nurses safe. [PDF]
Cipriano PF.
europepmc +1 more source
The matrix segment of the "Spanish flu" virus originated from intragenic recombination between avian and human influenza A viruses. [PDF]
He CQ, He M, He HB, Wang HM, Ding NZ.
europepmc +1 more source
Loss of E3 ligase HvST1 function substantially increases distal crossover frequency
Summary This study characterizes the function of a grass‐specific E3 ubiquitin ligase, HvST1, in regulating synapsis and crossover (CO) formation during meiosis in barley (Hordeum vulgare). In large‐genome cereals, COs are predominantly restricted to distal chromosomal regions, limiting genetic recombination and breeding flexibility.
Jamie Neil Orr +8 more
wiley +1 more source

