Results 61 to 70 of about 216,280 (244)

Flavia Kaba y Fernando Cid Lucas. Trampolín. Manual para aprender español a través de su literatura. Tirana: EDFA, 2024, 263 p. Recenzie de carte [PDF]

open access: yesEon
In the age of digitalization, the instantaneous transmission and reception of information, and the essentialization of the message, teaching literature in the Spanish as a Foreign Language (ELE) classroom seems to pose ever more challenges for teachers ...
Darius-Aurelian DRAGOMIR-COZMA
doaj   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan   +14 more
wiley   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

Juan Goytisolo in the Soviet Union [PDF]

open access: yesЛитературный факт
Juan Goytisolo (1931–2017) was the first Spanish writer of the new generation to attract Soviet attention since the defeat of the Republicans in the Spanish Civil War (1936–1939).
Kristina R. Buynova
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

The Role of the Other in the Construction of Identity: Considerations Around Martin Buber and Emmanuel Levinas

open access: yesReligions
By comparing Buber and Levinas, this article aims to clarify the constitution of the self as a place of identity. Both authors recognise, at first, that the self is only defined in relation to others and, ultimately, in relation to the You.
Teresa Aizpún
doaj   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

Integrating Patient‐Reported Quality Measures in Systemic Lupus Erythematosus: Development of the American College of Rheumatology Implementation Guide

open access: yesArthritis Care &Research, EarlyView.
Objective To support high‐quality, patient‐centered care for systemic lupus erythematosus (SLE), the American College of Rheumatology (ACR) developed evidence‐based measures incorporating clinical and patient‐reported outcome measures (PROMs). Using the Consolidated Framework for Implementation Research (CFIR), we conducted semistructured interviews ...
Catherine Nasrallah   +13 more
wiley   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

open access: yesArthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

Rigidity in Autism Spectrum Disorder (ASD): A Unified (Evolutionary) Account of Salient Linguistic and Non-Linguistic Characteristics

open access: yesAutism and Developmental Language Impairments
Autism spectrum disorder (ASD) typically exhibits stereotyped or repetitive behavior that can be described as rigid, but also certain characteristics in the domain of language that can equally be characterized as rigid. These include heightened, enhanced
Ljiljana Progovac   +1 more
doaj   +1 more source

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