Results 71 to 80 of about 101,679 (296)

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

Variation of relative complementizers in Yucatecan Spanish

open access: yes, 2022
The starting point of this article is the occurrence of determiner-less and bare que relative complementizers like (en) que, ‘(in) that’, instead of (en) el que, ‘(in) which’, in Yucatecan Spanish (southeast Mexico). While reference grammars treat complementizers with a determiner as the standard option, previous diachronic research has shown that ...
Auhagen, Christopher Patrick   +1 more
openaire   +2 more sources

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Structural and sociolectal limits of variability of que in Mexican Spanish noun clefts

open access: yesIsogloss
This paper investigates the structural and sociolectal limits of the use of non-standard “plain” que instead of the standard relativizer DET+que in Mexican Spanish noun clefts.
Patrick Auhagen, Jan Fliessbach
doaj   +1 more source

Interaction of Intraprocedural Antiplatelets and Intravenous Thrombolysis in Acute Intracranial Stenting: RESISTANT Registry Subanalysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes   +75 more
wiley   +1 more source

A Description of Tucumán Spanish Intonation in Argentina

open access: yesOpen Linguistics, 2017
This paper documents for the first time the intonation system of Tucumán Spanish, an understudied variety of Argentinian Spanish. Semi-spontaneous speech illustrating the intonation of main sentence types, i.e.
Terán Virginia, Ortega-Llebaria Marta
doaj   +1 more source

Differential Item Functioning on the Patient Health Questionnaire 8 by Disease Subtype, Language, Sex, and Age Among People With Systemic Sclerosis: A Scleroderma Patient‐Centered Intervention Network Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Somatic items used in depression assessments can potentially overlap with symptoms related to physical illness, including systemic sclerosis (SSc). No studies have looked at whether somatic depression items may be influenced by diffuse versus limited SSc disease subtypes, which are associated with varying degrees of symptom presentation.
Sophie Hu   +110 more
wiley   +1 more source

The Sociolinguistic Profile of Ser and Estar in Cuban Spanish: An Analysis of Oral Speech [PDF]

open access: yes, 2017
Copyright 2017 by Georgetown University Press. Manuel Dfaz-Campos, Iraida Galarza, and Gibran Delgado-Dfaz, "8. The Sociolinguistic Profile of Ser and Estar in Cuban Spanish". From Cuban Spanish Dialectology: Variation, Comact, and Change, Alejandro Cuza,
Díaz-Campos, Manuel   +2 more
core  

Ralph Penny, Variation and change in Spanish. Cambridge University Press, Cambridge, 2000; xiv + 284 pp.

open access: yesNueva Revista de Filología Hispánica, 2002
Se reseñó el libro: Variation and change in Spanish.
Pedro Martín Butragueño
doaj   +1 more source

Variation in Andorran Spanish past perfectives

open access: yesSpanish in Context, 2023
AbstractRomance varieties differ in their usage of preterit and present perfect verb tenses. Both are past perfectives, but whereas Portuguese uses the preterit in most contexts, spoken French prefers the present perfect. Peninsular Spanish lies between the two, though evidence indicates that the present perfect is becoming the default past perfective (
openaire   +3 more sources

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