Results 41 to 50 of about 48,244 (304)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Completely Independent Spanning Trees in k-Th Power of Graphs
Discussiones Mathematicae Graph Theory, 2018 Let T1, T2, . . . , Tk be spanning trees of a graph G. For any two vertices u, v of G, if the paths from u to v in these k trees are pairwise openly disjoint, then we say that T1, T2, . . . , Tk are completely independent. Araki showed that the square of
Hong Xia
doaj +1 more source
Constructing Independent Spanning Trees on Generalized Recursive Circulant Graphs
IEEE Access, 2021 The generalized recursive circulant networking can be widely used in the design and implementation of interconnection networks. It consists of a series of processors, each is connected through bidirectional, point-to-point communication channels to ...
Dun-Wei Cheng +2 more
doaj +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
An Edge-Swap Heuristic for Finding Dense Spanning Trees
Theory and Applications of Graphs, 2016 Finding spanning trees under various restrictions has been an interesting question to researchers. A "dense" tree, from a graph theoretical point of view, has small total distances between vertices and large number of substructures.
Mustafa Ozen +3 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano +11 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source
Brain Tumor Segmentation Based on Minimum Spanning Tree
Frontiers in Signal Processing, 2022 In this paper, we propose a minimum spanning tree-based method for segmenting brain tumors. The proposed method performs interactive segmentation based on the minimum spanning tree without tuning parameters.
Simeon Mayala +9 more
doaj +1 more source
Innovating Aircraft Repair Processes: The Role of Digitalization in Sustainability
Advanced Engineering Materials, EarlyView.This research explores how digitalization—by storing detailed non‐destructive testing data in structured DICONDE databases and creating a standard data model of the component—innovates aviation maintenance and repair processes. Coupled with a developed state‐based simulation model, it enables data‐driven, sustainable repair strategies that reduce waste,
Johanna Aigner +3 more
wiley +1 more source