Results 101 to 110 of about 16,728 (249)
Advanced Science, EarlyView.Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu +10 more
wiley +1 more source
E3S Web of Conferences, 2017 This paper discusses the problem associated with accidents in the aerial line (AL) ultra-high voltage (UHV) due to its big length. In lines with a voltage of 500-1150 kV the overwhelming proportion of trips (98%) is caused by single-phase short circuit ...
Krasil'nikova Tatyana, Jononaev Saiyod
doaj +1 more source
, 1973 labrador n... in consequence of which many tons of rocks fall down as soon as the ice is thawed. White spar is very common; and several samples of that beautiful one called Labrador spar, has been picked up by the Esquimaux, of which there is one
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Cell‐Selective Delivery of RIBOTACs via an Anti‐EGFR Nanobody for Pancreatic Cancer Treatment
Advanced Science, EarlyView.This study introduces an innovative strategy for the tumor‐selective catalytic degradation of oncogenic non‐coding RNA by interfacing a ribonuclease‐recruiting small molecule (RIBOTAC) with an EGFR‐targeting nanobody via a CTSB (Cathepsin B)‐responsive linker.
Tianli Luo +15 more
wiley +1 more source
Advanced Science, EarlyView.A bio‐inspired side‐chain branching strategy is developed to orchestrate a dual noncovalent conformational locking (NoCL) network, enabling the construction of perfectly planar NIR‐II phototheranostic aggregates. Such structural precision maximizes light‐harvesting efficiency and optimizes exciton dynamics, ensuring synchronized enhancements in NIR‐II ...
Cheng Lu +11 more
wiley +1 more source
Advanced Science, EarlyView.NSD2 coordinates the neurogenic‐to‐gliogenic transition in the developing neocortex through H3K36me2‐dependent activation of EGFR–ERK signaling. Loss of NSD2 disrupts astroglial and oligodendroglial development, whereas ERK activation rescues gliogenic defects in vitro and in vivo.
Hanxue Chen +7 more
wiley +1 more source
Advanced Science, EarlyView.Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries +25 more
wiley +1 more source
, 1965 spar nThe scene for such a fight was either the pond or the field, no matter how biting the frost; stripped to a "spar" the duel was the test of the best man.PRINTED ITEM DNE-citW. J.
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, 1981 The contents of the stored data sets of the SPAR (space processing applications rocket) finite element structural analysis system are documented. The data generated by each of the system's processors are stored in a data file organized as a library. Each
Cunningham, S. W.
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Advanced Science, EarlyView.Using a minimal set of experimentally labeled antimicrobial and non‐antimicrobial peptides, we reconstruct the effective lipid composition of a pathogenic membrane ‐demonstrated at the example of bacterial membranes‐ through a physics‐based evolutionary molecular dynamics (Evo‐MD) approach. Optimization based on peptide insertion reveals broad‐spectrum
Maximilian Krebs, Herre Jelger Risselada
wiley +1 more source