Results 201 to 210 of about 55,467 (261)

SPARK

Farumashia, 2016
openaire   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Social and physical activity as rehabilitation for preschool kids with cancer-study protocol for a randomized controlled trial. [PDF]

Front Pediatr
Pouplier A, Fridh MK, Schmidt-Andersen P, Hoffmann M, Winther H, Christensen J, Larsen HB.   +6 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Ca2+ signalling in cardiac muscle: the importance of balances. [PDF]

Europace
Niggli E, Gomez AM.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Author Correction: Performance enhancement of electrochemical discharge micromachining of borosilicate glass using nitrogen gas assistance. [PDF]

Sci Rep
Tamilperuvalathan S, Varadharaju V, Rajamohan S, Balasubramanian D, Kale U, Kilikevičius A.   +5 more
europepmc   +1 more source

Igniting the spark in six countries to transform the trajectory of postpartum hemorrhage across the globe: An overview of the AMPLI-PPHI project. [PDF]

Int J Gynaecol Obstet
Roman E.
europepmc   +1 more source

Castl: robust identification of spatially variable genes in spatial transcriptomics via an ensemble-based framework. [PDF]

Brief Bioinform
Yu Y, Yang J, He PA, Zheng X.
europepmc   +1 more source

The green spark of partial reform: Evidence from China's electricity market experiment. [PDF]

PNAS Nexus
Hao X, Sun A, Song F, Zheng H, Zhang L.
europepmc   +1 more source