Results 151 to 160 of about 363,392 (196)

ProteoSeeker: A Feature‐Rich Metagenomic Analysis Tool for Accessible and Comprehensive Metagenomic Exploration

open access: yesAdvanced Science, EarlyView.
ProteoSeeker is a new metagenomic analysis tool that accelerates protein discovery. By automating key steps, it reduces computational complexity and enables comprehensive dataset analysis, performing protein identification, screening based on user‐defined protein families, and taxonomic analysis.
Georgios Filis   +6 more
wiley   +1 more source

Dialogues about the practice of science. [PDF]

open access: yesProc Natl Acad Sci U S A
Shiffrin RM   +3 more
europepmc   +1 more source

Single‐Cell Analysis Clarifies Pathological Heterogeneity in Tenosynovial Giant Cell Tumor and Identifies Biomarkers for Predicting Disease Recurrence

open access: yesAdvanced Science, EarlyView.
MP3 tumor cells, a specific subpopulation of tumor cells in D‐TGCT, regulated the differentiation of CD34+ Fbs into MMP3+ Fbs and APOE+ Fbs through COL6A3 − (ITGAV + ITGB8) interaction. APOE+ Fbs activated IL‐1B+CCL20+ Mφs through the CXCL12/CXCR4 axis. IL‐1B+CCL20+ Mφs and MMP3+ Fbs participated in the local invasion of D‐TGCT.
Yubin Xie   +15 more
wiley   +1 more source

Recent advances in spatially variable gene detection in spatial transcriptomics. [PDF]

open access: yesComput Struct Biotechnol J
Das Adhikari S, Yang J, Wang J, Cui Y.
europepmc   +1 more source

Chronic, Battery‐Free, Fully Implantable Multimodal Spinal Cord Stimulator for Pain Modulation in Small Animal Models

open access: yesAdvanced Science, EarlyView.
This work introduces wireless‐powered fully implantable spinal cord stimulation (SCS) in freely moving animal models, supporting diverse ethological paradigms. kHz stimulation with real‐time digital programming offers versatile, dynamically optimized therapy. Scalable fabrication ensures high N studies and seamless translation.
Allie J. Widman   +11 more
wiley   +1 more source

Li+ Diffusion in LinCoNb2O6 (0 < n ≤ 6) Anode with High Capacity Density: Fast Kinetics and Mechanistic Insights

open access: yesAdvanced Science, EarlyView.
CoNb2O6 with 6 Li+/e⁻ reaction and high theoretical capacity density of 472 mA g−1, exhibited exceptional rate capability and cycling stability, which is attributed to dual Li+ solid diffusion mechanisms, namely direct‐hopping mechanism in LinCoNb2O6 (0 ≤ n ≤ 3) and knock‐off mechanism in LinCoNb2O6 (3 < n ≤ 6).
Yimo Xiang   +3 more
wiley   +1 more source

Multi‐Shank 1024 Channels Active SiNAPS Probe for Large Multi‐Regional Topographical Electrophysiological Mapping of Neural Dynamics

open access: yesAdvanced Science, EarlyView.
This research article introduces a novel CMOS neural probe with 1024 channels distributed across eight shanks. The SiNAPS probe allows for the simultaneous recording of both local field potentials and action potentials in large brain areas. The probe's design allows for detailed mapping and linking neural dynamics and population unit activity, as ...
Gian Nicola Angotzi   +13 more
wiley   +1 more source

Explainable Deep Multilevel Attention Learning for Predicting Protein Carbonylation Sites

open access: yesAdvanced Science, EarlyView.
Selective carbonylation sites (SCANS) are conceptualized, designed, evaluated, and released. SCANS captures segment‐level, protein‐level, and residue embeddings features. It utilizes elaborate loss function to penalize cross‐predictions at the residue level.
Jian Zhang   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy