Results 71 to 80 of about 724,897 (308)
Positive definite estimation of large covariance matrix using generalized nonconvex penalties
IEEE Access, 2016 This paper addresses the issue of large covariance matrix estimation in a high-dimensional statistical analysis. Recently, improved iterative algorithms with positive-definite guarantee have been developed.
Fei Wen +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Robust and Sparse Regression via γ-Divergence
Entropy, 2017 In high-dimensional data, many sparse regression methods have been proposed. However, they may not be robust against outliers. Recently, the use of density power weight has been studied for robust parameter estimation, and the corresponding divergences ...
Takayuki Kawashima, Hironori Fujisawa
doaj +1 more source
IEEE Access, 2020 Since the cost of labeling data is getting higher and higher, we hope to make full use of the large amount of unlabeled data and improve image classification effect through adding some unlabeled samples for training.
Wenjuan Zhang +2 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Sparse kernel modelling: a unified approach
, 2007 A unified approach is proposed for sparse kernel data modelling that includes regression and classification as well as probability density function estimation. The orthogonal-least-squares forward selection method based on the leave-one-out test criteria
Hong, X., Harris, C.J., Chen, S.
core +1 more source
Dictionary-Based Low-Rank Approximations and the Mixed Sparse Coding Problem
Frontiers in Applied Mathematics and Statistics, 2022 Constrained tensor and matrix factorization models allow to extract interpretable patterns from multiway data. Therefore crafting efficient algorithms for constrained low-rank approximations is nowadays an important research topic.
Jeremy E. Cohen
doaj +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source