ERα–PADI4–CXCL8 Axis Drives MDSC‐Mediated Immune Evasion in Anaplastic Thyroid Carcinoma
Advanced Science, EarlyView.MAPK‐driven ligand‐independent ERα activation drives PADI4 transcription and translation. This enzyme then modifies CXCL8 chemokines through citrullination, generating a potent chemoattractant gradient specifically for myeloid‐derived suppressor cells.
Dongdong Zhang +5 more
wiley +1 more source
An Adaptive Grouping Method for Efficient Multi-Beam Testing of Phased Arrays. [PDF]
Sensors (Basel)Yan C, Zheng J, Gao H, Chen X.
europepmc +1 more source
Disentangling Heterogeneous Molecular Networks for Multi‐Omics‐Driven Cancer Driver Discovery
Advanced Science, EarlyView.DRIVE integrates PPI topology and pan‐cancer multi‐omics profiles through dual‐view graph disentanglement, contrastive representation learning, and joint optimization. Across six PPI networks, DRIVE outperforms ten baselines and remains robust to structural and annotation perturbations.
Xinjing Gong +8 more
wiley +1 more source
An Interpretable Deep-Unfolding Network for Real-Time Simultaneous Multi-Beam Synthesis in Sparse Phased-MIMO Radar. [PDF]
Sensors (Basel)Ma Z, Pei Z, Wei W, Luo Z, Yue Z.
europepmc +1 more source
Sparse array angle estimation using reduced-dimension ESPRIT-MUSIC in MIMO radar. [PDF]
ScientificWorldJournal, 2013 Zhang C, Pang Y.
europepmc +1 more source
qcGEM: A Graph‐Based Molecular Representation With Quantum Chemistry Awareness
Advanced Science, EarlyView.In this work, we introduce qcGEM, a quantum‐chemistry‐aware graph‐based embedding of molecules that incorporates physical priors into molecular representation learning. Through a specially designed model architecture to adequately process quantum chemistry information as well as three‐dimensional molecular geometry, qcGEM provides a compact, physics ...
Haoyu Wang +3 more
wiley +1 more source
High-Accuracy Off-Grid Sparse Bayesian Learning with Reliability-Guided Inference for Direction-of-Arrival Estimation. [PDF]
Sensors (Basel)He W, Wang H, Zhao H, Shi Y.
europepmc +1 more source
Q‐LEAP: Millisecond Hyperdimensional Optimization for Full‐Spectrum Optical Metamaterials
Advanced Science, EarlyView.Q‐LEAP integrates physics‐informed residual machine learning with factorization‐machine‐encoded quantum annealing to design full‐spectrum optical metamaterials. It explores a 2108 design space and, in a single 2.56 ms annealing step, reaches 85.83% of the theoretical FoM limit, enabling selective 5‐8 µm emission with 3–5 and 8–14 µm suppression and ∼40×
Zikang Guo +3 more
wiley +1 more source
Artificial sparse neuron dendrites for visual information inference. [PDF]
Sci AdvWang R +10 more
europepmc +1 more source