Generating Dynamic Structures Through Physics‐Based Sampling of Predicted Inter‐Residue Geometries
While static structure prediction has been revolutionized, modeling protein dynamics remains elusive. trRosettaX2‐Dynamics is presented to address this challenge. This framework leverages a Transformer‐based network to predict inter‐residue geometric constraints, guiding conformation generation via physics‐based iterative sampling. The resulting method
Chenxiao Xiang +3 more
wiley +1 more source
Cohort profile: The SAIL long-term conditions e-cohort (SLTC cohort) investigating area-level changes in healthcare resource use in Wales. [PDF]
Osborne T +4 more
europepmc +1 more source
Poly[2‐(methacryloyloxy)ethyl]dimethyl‐(3‐sulfopropyl)ammonium hydroxide‐based organohydrogels are formed via nonsolvent‐induced gelation, featuring tunable viscoelasticity. Functional fillers (MXene nanosheets, magnetic NdFeB microparticles) enable electrical, magnetic, and mechanical responsiveness for applications in mechano‐tunable electromagnetic ...
Ziyue Miao +4 more
wiley +1 more source
Rapid and gentle volumetric imaging of host-pathogen interactions in salmon skin cells using projective oblique plane microscopy. [PDF]
Sommernes JR +2 more
europepmc +1 more source
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang +7 more
wiley +1 more source
Reconstruction algorithm for photoacoustic tomography based on the L-alternating direction method of multipliers model. [PDF]
Wang X, Ren X, Wang H.
europepmc +1 more source
Federated Learning Driven Sparse Code Multiple Access in V2X Communications [PDF]
Zhen Chen +5 more
openalex +1 more source
Joint sparse graph over GF( q ) for code division multiple access systems [PDF]
Lei Wen, Man Su
openalex +1 more source
Radiation induces polyploid giant cancer cells (PGCCs) that regenerate tumors through virus‐like budding. This process depends on a SNCG–FLOT2–CHMP4B signaling axis functioning in lipid raft microdomains. Disrupting these domains using statins or anti‐PCSK9 antibodies blocks PGCC budding, suppresses tumor repopulation, and enhances radiotherapy ...
Zheng Deng +20 more
wiley +1 more source
Developing a comprehensive database and search tool for single-cell ATAC-seq data. [PDF]
Gibson-Khademi A +3 more
europepmc +1 more source

