Results 151 to 160 of about 13,553,800 (229)

Trends and Future Directions in Organic Chemistry for Drug Discovery

Chemistry – A European Journal, EarlyView.
Organic synthesis is being reshaped by the convergence of catalytic innovation, automation, artificial intelligence, and emerging therapeutic modalities. Late‐stage functionalization, photoredox and electrochemical methods, biocatalysis, flow chemistry, DELs, and proximity‐based drugs are examined as components of closed‐loop discovery.
Paweł Kozyra, Maciej Masłyk
wiley   +1 more source

Oral Second-Generation H1-Antihistamine Regimens for Allergic Rhinitis: Systematic Review and Network Meta-Analysis of Effects and Estimability. [PDF]

J Clin Med
Maya Viejo JD, Navarro I Ros FM, Trillo-Calvo E, Rodríguez LR.   +3 more
europepmc   +1 more source

Accelerating Frequency Response Measurements Through Sparse Data‐Driven Reconstruction Using the Loewner Framework

Chemie Ingenieur Technik, EarlyView.
Frequency response analysis is vital for electrochemical diagnostics but inherently time‐consuming. By building state‐space models from sparse frequency samples, the Loewner framework accurately reconstructs transfer functions and distribution of relaxation times (DRT), drastically cutting testing time without sacrificing accuracy.
Bansidhar Patel, Antonio Sorrentino, Ion Victor Gosea, Athanasios C. Antoulas, Tanja Vidaković‐Koch   +4 more
wiley   +1 more source

Learning sparse mixture‐of‐experts generalized linear models in ultrahigh dimensions

Canadian Journal of Statistics, EarlyView.
Abstract Motivated by the challenges of heterogeneity and high dimensionality in the analysis of modern data, we investigate continuous regularization methods for learning sparse mixture‐of‐experts generalized linear models (MoE‐GLM). Although there are foundational results about regularized estimators in a broad class of regression models including ...
Pengqi Liu, Abbas Khalili
wiley   +1 more source

RGCNMDA: pathway-bridged relational graph learning with adaptive multi-view fusion for human miRNA-disease association prediction. [PDF]

Bioinformatics
Hou C, Kone M, Xiang Y, Wang S.
europepmc   +1 more source

Non‐Invasive Estimation of Systemic Drug Exposure Using Exhaled Breath Metabolomics in Humans: A Translational Proof‐of‐Concept Study

Clinical Pharmacology &Therapeutics, EarlyView.
Accurate assessment of systemic drug exposure in humans remains challenging, as conventional approaches rely on intermittent blood sampling and laboratory‐based assays that are invasive and provide limited temporal resolution. Exhaled breath contains volatile and semi‐volatile compounds arising from drug metabolism and downstream biological processes ...
Kai Fricke, Diego M. Baur, Kapil Dev Singh, Felix Schmidt, Kathrin Müsch, Noriane A. Sievi, Marco Di Donato, Anton Schmick, Jonas Herth, Silvia Ulrich, Pablo Sinues, Marian Galovic, Malcolm Kohler   +12 more
wiley   +1 more source

ClusterApp to visualize, organize, and navigate metabolomics data. [PDF]

PLoS Comput Biol
Figueiredo da Costa VH, Karunarathne P, Borelli TC, Amatto IVDS, Ortega ML, Quinn RA, da Silva RR.   +6 more
europepmc   +1 more source

Developing Sustainable Innovations for Planet, Profits—And People: Mixed‐Methods Insights From the Textile Industry

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Sustainable innovations are increasingly recognized as promising avenues for businesses to tackle global sustainability challenges, expected to deliver ecological, social, and economic benefits. Yet social outcomes at the individual level remain underexplored, raising questions about whether such innovations fully realize their sustainability ...
Lisa Hollands, Celine Bökemeyer, Luca Haensse, Nick Lin‐Hi   +3 more
wiley   +1 more source

Disentangling factors affecting bacterial transcriptional regulatory network inference. [PDF]

iScience
Li G, Burrows JT, Lou XA, Palsson BO, Zielinski DC.   +4 more
europepmc   +1 more source

The Influence of Ethical Ideologies on Corporate Social Performance in Small and Medium‐Sized Enterprises in the United Kingdom

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Research addressing the microfoundations of corporate social performance (CSP) in small and medium‐sized enterprises (SMEs) remains sparse. This paper aims to investigate how SME managers' ethical ideology affects CSP and examines the mediating role of their CSR orientation (CSRO): economic, legal, ethical, and philanthropic.
Sarah Mohammad Suleiman Alsyoof, Vasa László, Tamás Sneider   +2 more
wiley   +1 more source