ABSTRACT Triple‐negative breast cancer (TNBC) represents the most aggressive subtype with limited therapeutic options and the poorest clinical outcomes. Using high‐resolution nUPLC‐QTOF‐MS/MS, we performed comprehensive proteomic profiling of TNBC cell lines representing disease progression stages: HCC‐1937 (stage IIB), HCC‐1599 (stage IIIA), and MDA ...
Claudia Sissely Chaviano‐Montes de Oca +7 more
wiley +1 more source
Secondary-Ion Mass Spectrometry Analysis of Pentosan Polysulfate. [PDF]
Hook AL +3 more
europepmc +1 more source
Traditional fishing with plant‐based piscicides is a global practice in decline, facing increasing restrictions. We investigated the chemical diversity of endemic Wikstroemia species historically used to stun or poison fish in Hawaiʻi. Using 1‐H‐NMR, principal component analysis, targeted HPLC, and target‐capture sequencing, we characterized compounds ...
Louise Winther +10 more
wiley +1 more source
Sparse neuronal C4 elevation induces network-wide transcriptomic and lipid-droplet remodeling in the cortical microenvironment. [PDF]
Sánchez-Carbonell M +13 more
europepmc +1 more source
Human Prostate Cell Lines: Derivation, Molecular Characteristics and Appropriate Use
ABSTRACT Background Research on prostate cancer and benign prostatic hyperplasia depends on a small number of immortalized human cell lines established between 1977 and 2001, most of them from advanced metastatic disease. The cell lines differ from one another in androgen receptor status, prostate‐specific antigen secretion, p53 status, karyotype and ...
Hamza Abohamra, Keenau Mark Pearce
wiley +1 more source
Cross-Species Behavioral Representation Learning Using Domain-Adversarial Adaptation on Wearable IMU Signals. [PDF]
Acı Çİ, Say F, Zaimoğlu EA.
europepmc +1 more source
Identification of Novel CD52+ Fibroblasts in Nodular Prostatic Hyperplasia
ABSTRACT Background Benign prostatic hyperplasia (BPH) and lower urinary tract symptoms are strongly associated with chronic prostate inflammation and stromal remodeling, yet the stromal cell programs that emerge during inflammatory, nodular remodeling remain incompletely defined. A Toxoplasma gondii infection model produces persistent inflammation and
Oliver R. Strobel +5 more
wiley +1 more source
SurvMarker: an R package for identifying survival-associated molecular features using PCA-based weighted scores. [PDF]
Gammune DH, Gu T.
europepmc +1 more source
Stage‐Specific Racial Disparities in Prostate Cancer Survival Outcomes
ABSTRACT Background Racial disparities in prostate cancer (PCa) survival are inconsistently reported. Methods We evaluated long‐term survival in 976 men from the NCI–Maryland PCa case‐control study, stratified by disease stage. Results There were no survival differences observed between African American (AA) and European American (EA) men with Stage 1 ...
Tsion Zewdu Minas +8 more
wiley +1 more source
Diversity and taxonomy of endophytic <i>Chaetomiaceae</i> (<i>Sordariales</i>) associated with roots of wild <i>Orchidaceae</i> in Brazil. [PDF]
Ramos DO +4 more
europepmc +1 more source

