Results 131 to 140 of about 15,887 (242)

Helmeted hornbill cranial kinesis: Balancing mobility and stability in a high‐impact joint

open access: yesThe Anatomical Record, Volume 309, Issue 5, Page 1299-1312, May 2026.
Abstract Prokinesis—in which a craniofacial joint allows the rostrum to move relative to the braincase—is thought to confer diverse advantages in birds, mostly for feeding. A craniofacial joint would, however, be a weak link if cranial stability is important. Paradoxically, we have identified a craniofacial joint in helmeted hornbills (Rhinoplax vigil),
Mike Schindler   +8 more
wiley   +1 more source

Next Generation 7 Tesla Arterial Spin Labeling With Rotated Spiral Acquisition Enables Mesoscale Resolution in 3D Brain Perfusion and Functional MRI

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 5, Page 2702-2717, May 2026.
ABSTRACT Purpose To achieve high resolution (≤ 1 mm isotropic) whole‐brain perfusion imaging at 7 T with next generation ASL pulse sequence, reconstruction algorithm, and MRI hardware. Methods We capitalized on three major innovations: (1) FLASH‐based pseudo‐Continuous ASL (pCASL) sequence with rotated golden‐angle stack‐of‐spirals (rGA‐SoS) sampling; (
Chenyang Zhao   +8 more
wiley   +1 more source

Possible association of short‐term complications and antimicrobial use in standing equine cheek tooth extractions 2018–2022

open access: yesEquine Veterinary Journal, Volume 58, Issue 3, Page 709-717, May 2026.
Abstract Background Despite growing concerns about antimicrobial resistance, prophylactic antimicrobials continue to be routinely administered in many procedures, including dental extractions. Further evidence‐based research is needed on whether their use influences post‐operative complication rates.
Marlies Schnierer   +4 more
wiley   +1 more source

Multiomics Research Strategies in Cancer: A Growing and Innovative Field

open access: yesMedComm, Volume 7, Issue 4, April 2026.
This review highlights multiomics strategies in cancer research, focusing on integration methods from genomics to microbiomics. Using colorectal cancer as a key example, it discusses biomarker discovery, data integration via deep learning, and the roles of single‐cell and spatial omics.
Zhenhua Du   +8 more
wiley   +1 more source

Feasibility Study for Dual Phase Free Breathing 3D bSSFP MRA With Preserved Eddy‐Current Tolerance With Adaptive k‐Space Lengths (PETAL) Acquisition

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 4, Page 2078-2091, April 2026.
ABSTRACT Purpose To demonstrate the feasibility of a novel dual‐phase self‐navigated, free‐breathing balanced steady‐state free‐precession whole‐heart MRA acquisition for aortic annulus size measurement using a Cartesian trajectory that mitigates eddy‐current artifacts by minimizing k‐space jumps between consecutive readouts with predictable scan times.
Tassia Ribeiro Salles Moura   +11 more
wiley   +1 more source

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

open access: yesChemistryOpen, Volume 15, Issue 4, April 2026.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel   +5 more
wiley   +1 more source

Sparse Logistic Regression-Based One-Bit SAR Imaging

open access: yesIEEE Transactions on Geoscience and Remote Sensing, 2023
Shaodi Ge   +4 more
openaire   +1 more source

Integration of Machine Learning With PBPK and QSAR Modeling Approaches to Facilitate Drug Discovery and Development

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 4, April 2026.
ABSTRACT This review examines the application of machine learning (ML) in physiologically based pharmacokinetic (PBPK) modeling through improved prediction of input parameters, particularly via quantitative structure–activity relationship (QSAR) models, for absorption, distribution, metabolism, and excretion (ADME) properties across drug development ...
Xinyue Chen, Zhoumeng Lin
wiley   +1 more source

Assessing Structure Collapse and Vegetation Loss After the 2025 Eaton Fire Using Optical Remote Sensing

open access: yesEarth and Space Science, Volume 13, Issue 4, April 2026.
Abstract On 7–8 January, 2025, the Eaton fire destroyed >9,000 structures and >40 km2 of forest in the northeastern region of the Los Angeles metropolitan area, California. Building damage was primarily assessed through ground investigations, a process that took several weeks due to hazardous conditions and the difficulty of accessing burnt areas. This
Solene L. Antoine
wiley   +1 more source

Intelligent Shanghai Typhoon Model (ISTM): A Diffusion‐Based Downscaling Emulator From AIFS to Kilometer‐Scale Regional Reanalysis for Typhoon Forecasts

open access: yesJournal of Geophysical Research: Machine Learning and Computation, Volume 3, Issue 2, April 2026.
Abstract Artificial‐intelligence weather prediction models have recently surpassed numerical models in large‐scale skill, but they still systematically underestimate typhoon intensity due to their reliance on coarse‐resolution training data from ERA5. To overcome this limitation, we constructed a bespoke 9‐km high‐resolution typhoon reanalysis (HiRes ...
Zeyi Niu   +8 more
wiley   +1 more source

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