Results 81 to 90 of about 726,041 (339)

Sparsity-control ternary weight networks

open access: yesNeural Networks, 2022
version 1 of SCA; accepted by journal "Neural Networks"; the final version could be a little different from this ...
Xiang Deng, Zhongfei Zhang
openaire   +4 more sources

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga   +2 more
wiley   +1 more source

Oversmoothing regularization with $\ell^1$-penalty term

open access: yesAIMS Mathematics, 2019
In Tikhonov-type regularization for ill-posed problems with noisy data, the penalty functionalis typically interpreted to carry a-priori information about the unknown true solution.We consider in this paper the case that the corresponding a-priori ...
Daniel Gerth, Bernd Hofmann
doaj  

Protein O‐glycosylation in the Bacteroidota phylum

open access: yesFEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns   +2 more
wiley   +1 more source

COLLAGE-BASED INVERSE PROBLEMS FOR IFSM WITH ENTROPY MAXIMIZATION AND SPARSITY CONSTRAINTS

open access: yesImage Analysis and Stereology, 2013
We consider the inverse problem associated with IFSM: Given a target function f, find an IFSM, such that its invariant fixed point f is sufficiently close to f in the Lp distance.
Herb Kunze   +2 more
doaj   +1 more source

Sparse FIR Filter Design Based on Signomial Programming

open access: yesElektronika ir Elektrotechnika, 2020
The goal of sparse FIR filter design is to minimize the number of nonzero filter coefficients, while keeping its frequency response within specified boundaries.
Maja Jurisic Bellotti, Mladen Vucic
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Case of a 35‐Year‐Old Man With Pain With Sneezing and Leg Weakness Causing Collapse

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This case details a 35‐year‐old man with no past medical history who presents with acute paraparesis and urinary retention in the setting of progressive paresthesias and weakness of his lower and upper extremities over several months. He was found to have longitudinally extensive transverse myelitis involving the cervical to mid‐thoracic cord ...
Joey Hsu   +3 more
wiley   +1 more source

A Systematic Evaluation of Recurrent Neural Network Models for Edge Intelligence and Human Activity Recognition Applications

open access: yesAlgorithms
The Recurrent Neural Networks (RNNs) are an essential class of supervised learning algorithms. Complex tasks like speech recognition, machine translation, sentiment classification, weather prediction, etc., are now performed by well-trained RNNs.
Varsha S. Lalapura   +3 more
doaj   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas   +18 more
wiley   +1 more source

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