Results 51 to 60 of about 582,597 (232)

Demonstration of an enhanced dosing pattern for debulking large and bulky unresectable tumors via differential hole‐size spatially fractionated radiotherapy

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose/objective We propose a novel lattice deployment for spatially fractionated radiotherapy (SFRT) treatments. In this approach, a larger diameter high‐dose sphere is centrally placed in the bulky tumor mass and surrounded by smaller diameter high‐dose spheres.
Joshua Misa   +2 more
wiley   +1 more source

Dosimetric evaluation and clinical application of collimated apertures with proton beam line scanning in stereotactic radiotherapy

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Stereotactic radiotherapy (SRT) is a highly effective treatment with precision for small, localized lesions. Proton therapy, characterized by the Bragg peak, offers superior dose conformity compared to photon‐based approaches. However, challenges remain in minimizing lateral penumbra and optimizing dose delivery, particularly for small
Chen‐Yu Chou   +3 more
wiley   +1 more source

Placebo Effect Sizes in Clinical Trials of Knee Osteoarthritis Using Intra‐Articular Injections of Biologic Agents

open access: yesArthritis Care &Research, EarlyView.
Objective Patients with knee osteoarthritis rely on symptomatic treatments, in which up to 75% of the pain reduction can be attributed to the placebo effect. This effect may vary based on treatment type (eg, biologics vs nonbiologic injection) and route of administration (eg, intra‐articular vs topical vs oral).
Johanna M. Borst   +5 more
wiley   +1 more source

Longitudinal Relationship Between Pain and Depression in People With Inflammatory Arthritis: A Narrative Review

open access: yesArthritis Care &Research, EarlyView.
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox   +3 more
wiley   +1 more source

Numerical Studies of Influencing Factors on the Homogeneity of the Powder Mixture during the Powder Spreading Process of Powder Bed Fusion–Laser Beam/Metal

open access: yesAdvanced Engineering Materials, EarlyView.
AISI 304L stainless steel powder is mixed with silicon nitride (Si3N4) powder and processed by PBF‐LB/M, allowing partial retention of Si3N4. The numerical approach effectively predicts the Si3N4 powder homogeneity and N content distribution on the powder bed. Recent studies have focused on the alloying of nitrogen (N) in high‐alloy stainless steels by
Yuanbin Deng   +7 more
wiley   +1 more source

Bridging Nature and Technology: A Perspective on Role of Machine Learning in Bioinspired Ceramics

open access: yesAdvanced Engineering Materials, EarlyView.
Machine learning (ML) is revolutionizing the development of bioinspired ceramics. This article investigates how ML can be used to design new ceramic materials with exceptional performance, inspired by the structures found in nature. The research highlights how ML can predict material properties, optimize designs, and create advanced models to unlock a ...
Hamidreza Yazdani Sarvestani   +2 more
wiley   +1 more source

A Novel Approach on Rapid Alloy Development of Tool Steels for Laser Powder Bed Fusion by In Situ Alloying

open access: yesAdvanced Engineering Materials, EarlyView.
A novel approach for alloy development in laser powder bed fusion is introduced. Instead of producing massive samples of one composition at a time, prepressed powder bed samples produced from powder mixtures are processed. Guidelines for the selection of precursor powders are developed.
Felix Großwendt   +6 more
wiley   +1 more source

Nanoparticle‐Coated X2CrNiMo17‐12‐2 Powder for Additive Manufacturing – Part I: Surface, Flowability, and Optical Properties of SiC, Si, and Si3N4 Coated Metal Powders

open access: yesAdvanced Engineering Materials, EarlyView.
Herein, silicon‐based nanoparticle coatings on X2CrNiMo17‐12‐2 metal powder are presented. The coating process scale, process parameters, nanoparticle size (65–200 nm) as well as the coating amount are discussed regarding powder properties. The surface roughness affects the flowability, while reflectance depends on the coating material and surface ...
Arne Lüddecke   +4 more
wiley   +1 more source

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