Results 11 to 20 of about 65,556 (241)

Extracellular Vesicles Define Discrete Nano-Based Niches Within the Human Haematopoietic System. [PDF]

J Extracell Vesicles
ABSTRACT Stem cell niches are complex multi‐signalling networks comprised of molecular cues and physical interactions, orchestrated by niche‐resident cells and the extracellular factors they produce. The bone niche specifically houses haematopoietic stem cells (HSCs), a critical cell type responsible for producing all blood and immune cells throughout ...
Grenier-Pleau IJ, Wells CJ, Holmes SM, Hall C, Vermeulen M, de Villiers CA, Penders J, Pedersen SV, Dick SA, Bonneil E, Slobodyanyuk M, Nagree MS, Kaur J, McNaughton AJM, Beaulieu J, Stevens MM, Xie SZ, Rauh MJ, Postovit LM, Knapp DJHF, Reimand J, Tyryshkin K, Thibault P, Craig AW, Rudan JF, Mann S, Chan EYW, Abraham SA.   +27 more
europepmc   +2 more sources

SPARTA: Spatial Acceleration for Efficient and Scalable Horizontal Diffusion Weather Stencil Computation [PDF]

International Conference on Supercomputing, 2023
Fast and accurate climate simulations and weather predictions are critical for understanding and preparing for the impact of climate change. Real-world climate and weather simulations involve the use of complex compound stencil kernels, which are ...
Gagandeep Singh, Alireza Khodamoradi, K. Denolf, Jack Lo, Juan G'omez-Luna, Joseph Melber, Andra Bisca, H. Corporaal, O. Mutlu   +8 more
semanticscholar   +1 more source

This is SpArta: Rigorous Optimization of Regionally Resolved Energy Systems by Spatial Aggregation and Decomposition [PDF]

Applied Energy, 2023
Energy systems with high shares of renewable energy are characterized by local variability and grid limitations. The synthesis of such energy systems, therefore, requires models with high spatial resolution. However, high spatial resolution increases the
C. Reinert, B. Nilges, N. Baumgärtner, A. Bardow   +3 more
semanticscholar   +1 more source

Hybrid Extracellular Vesicles for Efficient Loading and Functional Delivery of mRNA. [PDF]

J Extracell Vesicles
Hybrid extracellular vesicles (HEV) produced by EV‐LNP fusion enable efficient loading and functional delivery of mRNA. HEV integrated properties of both EV and LNP contributing to their excellent cell tolerability and acquired capacity of inducing endosomal escape.
Wang X, Munson MJ, Friis K, Marzeda A, Silva AM, Kohl F, Hultin L, Schiffelers RM, Dekker N.   +8 more
europepmc   +2 more sources

SPARTA: Signal Propagation-based Attack Recognition and Threat Avoidance for Automotive Networks

ACM Asia Conference on Computer and Communications Security, 2023
With wider availability of wireless interfaces and a rising integration of software, it becomes easier for attackers to access vehicular communication networks and exploit vulnerabilities in Electronic Control Units (ECUs). Once having compromised an ECU,
Oleg Schell, Marcel Kneib
semanticscholar   +1 more source

SPARTA: Efficient Open-Domain Question Answering via Sparse Transformer Matching Retrieval [PDF]

North American Chapter of the Association for Computational Linguistics, 2020
We introduce SPARTA, a novel neural retrieval method that shows great promise in performance, generalization, and interpretability for open-domain question answering.
Tiancheng Zhao, Xiaopeng Lu, Kyusong Lee
semanticscholar   +1 more source

Structural basis for ssDNA-activated NADase activity of the prokaryotic SPARTA immune system

bioRxiv, 2023
Argonaute proteins (Agos), which use small RNAs or DNAs as guides to recognize complementary nucleic acid targets, mediate RNA silencing in eukaryotes.
Jun-Tao Zhang, Xin-Yang Wei, N. Cui, Ruilin Tian, N. Jia   +4 more
semanticscholar   +1 more source

Use of iGlarLixi for the Management of Type 2 Diabetes in Japanese Clinical Practice: Prior Treatment Subgroup Analysis of the SPARTA Japan Study

Diabetes Therapy, 2023
Despite initially receiving oral treatment for their diabetes, many individuals with type 2 diabetes are unable to achieve their blood glucose targets and require treatment intensification as their disease progresses.
H. Miyoshi, M. Matsuhisa, D. Yabe, Yoko Takahashi, Y. Morimoto, Y. Terauchi   +5 more
semanticscholar   +1 more source

Tibrone, un armosta poco intraprendente? Note su uno spartano in Asia

Erga-Logoi, 2022
This paper focuses on the Spartan harmost Thibron, who led two expeditions to Asia in the first decade of the 4th century. It aims both to reconstruct the historical events, which are set in a context in which Sparta’s political action is characterised ...
Paolo A. Tuci
doaj   +1 more source

Herodotus’ past – Thucydides’ present – Xenophon’s future (ἀρχή, ἡγεμονία and imperialist tendencies in Classical Greece through the eyes of three great historians) [PDF]

Античный мир и археология, 2023
The article deals with some topics connected with imperialist tendencies in Greece of the last half of the 5th and the first half of the 4th century BC and with treatment of these developments in the work of the authors mentioned in the title ...
Surikov, Igor Evgenyevich
doaj   +1 more source