Highly purified cannabidiol (CBD) in CDKL5 deficiency disorder (CDD): Open‐label prospective study
Abstract Objective CDKL5 deficiency disorder (CDD) is an early‐onset developmental and epileptic encephalopathy characterized by frequent drug‐resistant seizures, cerebral visual impairment, motor dysfunction, and sleep and gastrointestinal disturbances.
Marco Perulli +12 more
wiley +1 more source
Pelvic Inflammatory Disease With Presumptive Tubo-Ovarian Abscess Presenting With Rectal Spasm. [PDF]
Larkins MC, Lanier AL, Smith C.
europepmc +1 more source
Abstract Objective Treatment selection for infantile epileptic spasms syndrome (IESS) is complex and multifaceted, and currently no electroencephalogram (EEG) biomarkers can guide this decision by predicting treatment response. We tested the predictive value of phase–amplitude coupling (PAC) as IESS patients are known to have elevated PAC.
Soudeh Mostaghimi +6 more
wiley +1 more source
Impact of Microvascular Spasm on Coronary Physiological Assessment - Insights From Angiography-Derived Index of Microcirculatory Resistance. [PDF]
Shimosato H +13 more
europepmc +1 more source
Spasm at the Entrance to the Œsophagus
A. B. Kelly
semanticscholar +1 more source
Loss of cyclin‐dependent kinase‐like 5 results in susceptibility to audiogenic seizures in mice
Abstract CDKL5 deficiency disorder (CDD) is a severe neurodevelopmental encephalopathy characterized by early‐onset, treatment‐resistant epilepsy. Mice lacking CDKL5 display several clinically relevant phenotypes, but spontaneous seizures are not consistently reported, and it is unknown if CDD model mice are susceptible to sensory stimulus‐triggered ...
Jordan Higgins +4 more
wiley +1 more source
Hemifacial Spasms with Unusual Neurovascular Compression Type: Arterial Cisternal Segment Offender. [PDF]
Lee HS, Park SW, Park SK, Park K.
europepmc +1 more source
Abstract Objective To investigate the frequency, predictors, and clinical implications of diagnostic reassessment in patients previously diagnosed with childhood‐onset epilepsy during the transition period to adult care at a tertiary epilepsy center. Methods We conducted a retrospective cohort study of 317 patients previously diagnosed with childhood ...
Tetsuhiro Fukuyama +9 more
wiley +1 more source
Segment-targeted peroral endoscopic myotomy for recurrent diffuse esophageal spasm with giant diverticula. [PDF]
Li LD, He DL, Zhong YS.
europepmc +1 more source
Wonder as a Gateway to Science Meaning‐Making: Primary Pupils’ Narrative Journeys
ABSTRACT This study explores how wonder fosters transformative learning in science education for pupils (11–12 years old), creating meaning about cycles in nature. As an emotional and epistemic trigger, wonder may bridge everyday experiences with abstract scientific concepts by stimulating curiosity and creativity. Through a narrative writing task, the
Pauline Book, Siri‐Christine Seehuus
wiley +1 more source

