Results 151 to 160 of about 132,081 (301)

Highly purified cannabidiol (CBD) in CDKL5 deficiency disorder (CDD): Open‐label prospective study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective CDKL5 deficiency disorder (CDD) is an early‐onset developmental and epileptic encephalopathy characterized by frequent drug‐resistant seizures, cerebral visual impairment, motor dysfunction, and sleep and gastrointestinal disturbances.
Marco Perulli   +12 more
wiley   +1 more source

Prediction of treatment response in infantile epileptic spasms syndrome using EEG phase–amplitude coupling

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Treatment selection for infantile epileptic spasms syndrome (IESS) is complex and multifaceted, and currently no electroencephalogram (EEG) biomarkers can guide this decision by predicting treatment response. We tested the predictive value of phase–amplitude coupling (PAC) as IESS patients are known to have elevated PAC.
Soudeh Mostaghimi   +6 more
wiley   +1 more source

Impact of Microvascular Spasm on Coronary Physiological Assessment - Insights From Angiography-Derived Index of Microcirculatory Resistance. [PDF]

open access: yesCirc Rep
Shimosato H   +13 more
europepmc   +1 more source

Spasm at the Entrance to the Œsophagus

open access: yesThe Journal of Laryngology Rhinology and Otology, 1919
A. B. Kelly
semanticscholar   +1 more source

Loss of cyclin‐dependent kinase‐like 5 results in susceptibility to audiogenic seizures in mice

open access: yesEpilepsia Open, EarlyView.
Abstract CDKL5 deficiency disorder (CDD) is a severe neurodevelopmental encephalopathy characterized by early‐onset, treatment‐resistant epilepsy. Mice lacking CDKL5 display several clinically relevant phenotypes, but spontaneous seizures are not consistently reported, and it is unknown if CDD model mice are susceptible to sensory stimulus‐triggered ...
Jordan Higgins   +4 more
wiley   +1 more source

Diagnostic reassessment in patients previously diagnosed with childhood‐onset epilepsy during the transition to adult care: A retrospective cohort study in a tertiary epilepsy center

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To investigate the frequency, predictors, and clinical implications of diagnostic reassessment in patients previously diagnosed with childhood‐onset epilepsy during the transition period to adult care at a tertiary epilepsy center. Methods We conducted a retrospective cohort study of 317 patients previously diagnosed with childhood ...
Tetsuhiro Fukuyama   +9 more
wiley   +1 more source

Wonder as a Gateway to Science Meaning‐Making: Primary Pupils’ Narrative Journeys

open access: yesFuture in Educational Research, EarlyView.
ABSTRACT This study explores how wonder fosters transformative learning in science education for pupils (11–12 years old), creating meaning about cycles in nature. As an emotional and epistemic trigger, wonder may bridge everyday experiences with abstract scientific concepts by stimulating curiosity and creativity. Through a narrative writing task, the
Pauline Book, Siri‐Christine Seehuus
wiley   +1 more source

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