Results 191 to 200 of about 132,025 (234)

Infantile spasms: Assessing the diagnostic yield of an institutional guideline and the impact of etiology on long‐term treatment response

Epilepsia, 2022
Neuroimaging and genetic testing have been proposed for diagnostic evaluation of infantile spasms (IS), establishing etiology in ~60% of multicenter IS cohorts.
N. Chourasia, Christopher J. Yuskaitis, M. Libenson, A. Bergin, Shanshan Liu, Bo Zhang, A. Poduri, C. Harini   +7 more
semanticscholar   +1 more source

Treatment of children with infantile spasms: A network meta‐analysis

Developmental Medicine & Child Neurology, 2022
We performed a systematic review and network meta‐analysis (NMA) to obtain comparative effectiveness estimates and rankings of non‐surgical interventions used to treat infantile spasms.
P. Jain, J. Sahu, Paul S. Horn, V. Chau, C. Go, Quenby Mahood, R. Arya   +6 more
semanticscholar   +1 more source

Infantile spasms

Current Treatment Options in Neurology, 2001
Infantile spasms is a catastrophic form of epilepsy found only in infants and young toddlers, with the peak incidence between 4 - 7 months of age. Estimated prevalence is 1 in 2000 - 6000 live births. There are many causes of infantile spasms, including tuberous sclerosis, hypoxic-ischaemic injury, congenital infectious diseases, inborn errors of ...
M, Wong, E, Trevathan
openaire   +5 more sources

Automatic detection of interictal ripples on scalp EEG to evaluate the effect and prognosis of ACTH therapy in patients with infantile spasms

Epilepsia, 2021
We aimed to explore the feasibility of using scalp‐recorded high‐frequency oscillations (HFOs) to evaluate the efficacy and prognosis of adrenocorticotropic hormone (ACTH) treatment in patients with infantile spasms.
Wei Wang, Hua Li, Jiaqing Yan, Herui Zhang, Xiaonan Li, S. Zheng, Jiaoyang Wang, Yue Xing, Lipeng Cheng, Donghong Li, Hua-mei Lai, Junda Qu, H. Loh, Fang Fang, Xiaofeng Yang   +14 more
semanticscholar   +1 more source

Evolution of Infantile Spasms to Lennox-Gastaut Syndrome: What Is There to Know?

Journal of Child Neurology, 2021
Objective: Children with infantile spasms may develop Lennox-Gastaut syndrome. The diagnostic criteria for Lennox-Gastaut syndrome are vague, and many experts use varying combinations of the following criteria for diagnosis: paroxysmal fast activity on ...
J. Nelson, S. Demarest, Jake Thomas, E. Juarez-colunga, K. Knupp   +4 more
semanticscholar   +1 more source

Cost‐effectiveness of adrenocorticotropic hormone versus oral steroids for infantile spasms

Epilepsia, 2021
To compare the effectiveness and cost‐effectiveness of adrenocorticotropic hormone (ACTH) and oral steroids as first‐line treatment for infantile spasm resolution, we performed a systematic review, meta‐analysis, and cost‐effectiveness study.
Iván Sánchez Fernández, Marta Amengual-Gual, Marina Gaínza-Lein, Cristina Barcia Aguilar, A. Bergin, Christopher J. Yuskaitis, C. Harini   +6 more
semanticscholar   +1 more source

Patterns of Brain Injury in Perinatal Arterial Ischemic Stroke and the Development of Infantile Spasms

Journal of Child Neurology, 2021
Introduction: Perinatal arterial ischemic stroke (PAIS) underlies approximately 10% of infantile spasms (IS). We aim to identify patterns of brain injury in ischemic stroke that may predispose infants to infantile spasms.
R. Srivastava, Oriana Shaw, Edward A. Armstrong, Francois-Dominique Morneau-Jacob, J. Yager   +4 more
semanticscholar   +1 more source

Whole‐exome sequencing and adrenocorticotropic hormone therapy in individuals with infantile spasms

Developmental Medicine & Child Neurology, 2021
To identify additional genes associated with infantile spasms using a cohort with defined infantile spasms.
S. Demarest, Jeff Calhoun, K. Eschbach, Hung-Chun Yu, D. Mirsky, Katie Angione, T. Shaikh, G. Carvill, T. Benke   +8 more
semanticscholar   +1 more source