Results 221 to 230 of about 4,523,910 (314)

spAttClu: a spatial domain clustering model leveraging spatially weighted graph attention and contrastive learning. [PDF]

Bioinformatics
Zhang T, Zhang R, Zhang H, Zhao Z, Wang R, Li S, Jiang Y, Wei B, Wang G.   +8 more
europepmc   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Spatial flows of urban carbon sequestration services in Chinese urban agglomerations. [PDF]

iScience
Pang Q, Xu J, Pei S, Zhou Y, Dong X.
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Mapping Immunity With Cutting-Edge Spatial Biology and Tissue Cytometry Innovations. [PDF]

MedComm (2020)
Cárdenas-Piedra L, Samuel SG, Mungenast F, Yasothkumar D, Ecker RC, Batra J.   +5 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Hospitals alike, hospitals different: spatial clustering of inequality around Boston's hospitals. [PDF]

Front Sociol
Karduz EK.
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Immune Spatial Organization Predicts Distant Metastasis Risk in Aggressive Localized Prostate Cancer. [PDF]

Clin Cancer Res
Yang DD, Abdelnaser A, Haas AJ, Wala J, Barney AA, Saad E, Crowdis JP, Ricker CA, Awad S, Gurel B, Park J, King MT, Nguyen PL, Choueiri TK, Einstein DJ, Balk SP, Tewari AK, de Bono JS, Salari K, Taplin ME, Wu CL, Van Allen EM.   +21 more
europepmc   +1 more source