Results 51 to 60 of about 1,470,342 (248)

Operationalising “loveability”: an interdisciplinary approach to enriching quality of life experiences in cities through creative cultural spaces

open access: yesFrontiers in Built Environment
Loveability represents an emerging answer for enriching urban quality of life. The idea prioritises city dwellers’ emotional connections with psycho-spatial aspects of cities, beyond mere infrastructure, functionality, or services (“liveability”), which ...
Mizan Rambhoros   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The Chronotope of Home in The Rainbow: Place, Time and Identity

open access: yesÉtudes Lawrenciennes
Home in contemporary culture is acquiring ontological value due to our changing globalized world. In Lawrence’s fiction, the concept of home is an important metaphor of self and identity.
Marina Ragachewskaya
doaj   +1 more source

Persistent Spatial Patterns of Listeria monocytogenes and Salmonella enterica Concentrations in Surface Waters: Empirical Orthogonal Function Analysis of Data from Maryland

open access: yesApplied Sciences, 2022
High spatiotemporal variability of pathogen concentrations in surface waters complicates the design and interpretation of microbial water quality monitoring.
Seongyun Kim   +11 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

County-Level Radon and Incidence of Female Thyroid Cancer in Iowa, New Jersey, and Wisconsin, USA

open access: yesToxics, 2018
Background: Few studies have investigated the association between radon and thyroid cancer despite the sensitivity of the thyroid gland to radiation. Our goal is to investigate the association between county-level radon and incidence of female thyroid ...
Caroline Oakland, Jaymie R. Meliker
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Biophysical, Spatial, Functional, and Constructive Analysis of the Pre-Hispanic Terraces of the Ancient City of Pisaq, Cusco, Peru, 2024

open access: yesHeritage
The aim of the research is to examine the biophysical, spatial, functional, and structural components of the pre-Hispanic terracing systems located in the ancient city of Pisaq, considering the impacts of tourism, geological instability, and cultural ...
Francis Huaman   +7 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

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