Results 1 to 10 of about 25,930,960 (264)

Spatial analysis with SPIAT and spaSim to characterize and simulate tissue microenvironments

Nature Communications, 2023
Spatial proteomics technologies have revealed an underappreciated link between the location of cells in tissue microenvironments and the underlying biology and clinical features, but there is significant lag in the development of downstream analysis ...
Yuzhou Feng, Tianpei Yang, John Zhu, Mabel Li, M. Doyle, Volkan Ozcoban, Greg T. Bass, A. Pizzolla, Lachlan Cain, Sirui Weng, Anupama Pasam, Nikolce Kocovski, Yu-Kuan Huang, S. Keam, T. Speed, P. Neeson, R. Pearson, S. Sandhu, D. Goode, A. Trigos   +19 more
semanticscholar   +1 more source

High resolution mapping of the tumor microenvironment using integrated single-cell, spatial and in situ analysis

Nature Communications, 2023
Single-cell and spatial technologies that profile gene expression across a whole tissue are revolutionizing the resolution of molecular states in clinical samples. Current commercially available technologies provide whole transcriptome single-cell, whole
Amanda Janesick, Robert Shelansky, Andrew D. Gottscho, Florian Wagner, Stephen R. Williams, Morgane Rouault, Ghezal Beliakoff, Carolyn A Morrison, Michelli F Oliveira, Jordan Sicherman, Andrew Kohlway, Jawad Abousoud, T. Drennon, Seayar Mohabbat, Sarah E. B. Taylor   +14 more
semanticscholar   +1 more source

Squidpy: a scalable framework for spatial omics analysis

Nature Methods, 2022
Spatial omics data are advancing the study of tissue organization and cellular communication at an unprecedented scale. Flexible tools are required to store, integrate and visualize the large diversity of spatial omics data.
G. Palla, Hannah Spitzer, Michal Klein, David S. Fischer, A. C. Schaar, L. B. Kuemmerle, Sergei Rybakov, I. Ibarra, Olle Holmberg, Isaac Virshup, M. Lotfollahi, Sabrina Richter, Fabian J Theis   +12 more
semanticscholar   +1 more source

Drought Risk to Agricultural Systems in Zimbabwe: A Spatial Analysis of Hazard, Exposure, and Vulnerability

Sustainability, 2020
The devastating impacts of drought are fast becoming a global concern. Zimbabwe is among the countries more severely affected, where drought impacts have led to water shortages, declining yields, and periods of food insecurity, accompanied by economic ...
Janna Frischen, I. Meza, D. Rupp, Katharina Wietler, M. Hagenlocher   +4 more
semanticscholar   +1 more source

Giotto: a toolbox for integrative analysis and visualization of spatial expression data

Genome Biology, 2021
Spatial transcriptomic and proteomic technologies have provided new opportunities to investigate cells in their native microenvironment. Here we present Giotto, a comprehensive and open-source toolbox for spatial data analysis and visualization.
Ruben Dries, Qian Zhu, Rui Dong, C. L. Eng, Huipeng Li, Kan Liu, Yuntian Fu, T. Zhao, Arpan Sarkar, Feng Bao, R. George, N. Pierson, L. Cai, Guocheng Yuan   +13 more
semanticscholar   +1 more source

Airbnb Offer in Spain - Spatial Analysis of the Pattern and Determinants of Its Distribution

ISPRS Int. J. Geo Inf., 2019
The rising number of homes and apartments rented out through Airbnb and similar peer-to-peer accommodation platforms cause concerns about the impact of such activity on the tourism sector and property market.
C. Adamiak, Barbara Szyda, Anna Dubownik, D. Álvarez   +3 more
semanticscholar   +1 more source

Interpretable Deep Learning for Spatial Analysis of Severe Hailstorms

Monthly Weather Review, 2019
Deep learning models, such as convolutional neural networks, utilize multiple specialized layers to encode spatial patterns at different scales. In this study, deep learning models are compared with standard machine learning approaches on the task of ...
D. Gagne, S. E. Haupt, D. Nychka, G. Thompson   +3 more
semanticscholar   +1 more source

pavo 2.0: new tools for the spectral and spatial analysis of colour in R

bioRxiv, 2018
Biological colouration presents a canvas for the study of ecological and evolutionary processes. Enduring interest in colour-based phenotypes has driven, and been driven by, improved techniques for quantifying colour patterns in ever-more relevant ways ...
Rafael Maia, H. Gruson, J. Endler, T. White   +3 more
semanticscholar   +1 more source

Geographic Information Systems, spatial analysis, and HIV in Africa: A scoping review

PLoS ONE, 2019
Introduction Geographic Information Systems (GIS) and spatial analysis are emerging tools for global health, but it is unclear to what extent they have been applied to HIV research in Africa.
Danielle C. Boyda, Samuel B Holzman, Amanda Berman, M. Grabowski, L. Chang, L. Chang   +5 more
semanticscholar   +1 more source

Advances in spatial transcriptomics and related data analysis strategies

Journal of Translational Medicine, 2023
Spatial transcriptomics technologies developed in recent years can provide various information including tissue heterogeneity, which is fundamental in biological and medical research, and have been making significant breakthroughs.
Jun Du, Yu-chen Yang, Zhi-Jie An, Ming-hui Zhang, Xue-Hang Fu, Zoufang Huang, Ye Yuan, Jian Hou   +7 more
semanticscholar   +1 more source