Results 61 to 70 of about 239,117 (240)

Spatio-temporal variations of licensed doctor distribution in China: measuring and mapping disparities

BMC Health Services Research, 2020
Background The licensed doctor misdistribution is one of the major challenges faced by China. However, this subject remains underexplored as spatial distribution characteristics (such as spatial clustering patterns) have not been fully mapped out by ...
Bin Zhu, Chih-Wei Hsieh, Ying Mao
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Spatial and Temporal Distribution Characteristics of Dust Devils in the Qaidam Basin

Gaoyuan qixiang
Dust aerosols are significant components of atmospheric aerosols， and they play a crucial role in global weather and climate changes through radiative effects and the formation of cloud and precipitation.The impact of dust devils on the worldwide ...
Mengyuan WANG, Qian HUANG, Huiren LIAO, Yongpeng ZHANG, Kun GUO   +4 more
doaj   +1 more source

Spatial and Temporal Characteristics of Drought in Baiyangdian Basin Based on SPI

Shuitu baochi yanjiu, 2022
In order to explore the temporal and spatial evolution characteristics of drought in the Baiyangdian Basin, with a background of climate change, based on the 0.1° resolution precipitation grid data in the study area from 1979 to 2018, the Standardised ...
LIU Congwei, HU Shanshan, ZHANG Tao, YANG Zhan   +3 more
doaj  

Towards malaria prediction in Sri Lanka. modelling spatial and temporal variability of malaria case counts [PDF]

, 2008
This thesis was motivated by the need of the Anti Malaria Campaign (AMC) of Sri Lanka for malaria risk maps and malaria case number predictions to assist in the planning for malaria control.
Briët, Olivier J.T.
core   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Spatial-temporal characteristics of cropland distribution and its landscape fragmentation in China

Farming System
Analysing China's cropland changes highlights the intertwined dynamics of urbanization, industrialization, and ecological policies, offering insights into cropland efficiency and advancing agricultural modernization.
Xing Wang, Jia-Qi Hao, Zhen-Zhong Dai, Shahzad Haider, Sen Chang, Zhi-Yuan Zhu, Jia-jia Duan, Guang-Xin Ren   +7 more
doaj   +1 more source