Results 61 to 70 of about 441,505 (298)

TEST: A Tropic, Embodied, and Situated Theory of Cognition [PDF]

, 2013
TEST is a novel taxonomy of knowledge representations based on three distinct hierarchically organized representational features: Tropism, Embodiment, and Situatedness.
Fischer, Martin, Kessler, Klaus, Myachykov, Andriy, Scheepers, Christoph   +3 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Enumeration and Alertness in Developmental Dyscalculia

Journal of Cognition, 2019
Enumeration, the ability to report an amount of elements, differs as a function of range. Subitizing (quantities 1–4) is an accurate and quick process with reaction times (RTs) minimally affected by the number of presented elements within its range.
Yarden Gliksman, Avishai Henik
doaj   +1 more source

Representation, space and Hollywood Squares: Looking at things that aren't there anymore [PDF]

, 2000
It has been argued that the human cognitive system is capable of using spatial indexes or oculomotor coordinates to relieve working memory load (Ballard, Hayhoe, Pook & Rao, 1997) track multiple moving items through occlusion (Scholl & Pylyshyn, 1999) or
Richardson, Daniel, Spivey, Michael
core   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

City rats: From rat behaviour to human spatial cognition in urban environments [PDF]

, 2010
The structure and shape of an urban environment influence our ability to find our way about in the city^1-2^. Indeed, urban designers who face the challenge of planning environments that facilitate wayfinding^3^, have a consequent need to understand the ...
David Eilam, Juval Portugali, Osnat Yaski   +2 more
core   +1 more source

Evidence for unusual spatial location coding in Williams syndrome: An explanation for the local bias in visuo-spatial construction tasks? [PDF]

, 2005
Individuals with Williams syndrome (WS) display poor visuo-spatial cognition relative to verbal abilities. Furthermore, whilst perceptual abilities are delayed, visuo-spatial construction abilities are comparatively even weaker, and are characterised by ...
Akshoomoff, Ballard, Bellugi, Bihrle, Bowerman, Brown, Christopher Jarrold, Clark, Emily K. Farran, Farran, Farran, Hayward, Hoffman, Huttenlocher, Koenig, Kosslyn, Kosslyn, Kramer, Lagers-van Haselen, Lenhoff, Mervis, Mervis, Morris, Navon, Nickerson, Philips, Plumert, Poulton, Raven, Rossen, Sandberg, Shah, Wechsler, Woliver   +33 more
core   +3 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Your space or mine? : Mapping self in time [PDF]

, 2012
Peer reviewedPublisher ...
A D’Argembeau, A D’Argembeau, A Kranjec, A Torralbo, A Vallesi, AL Betz, B Tversky, Brittany M. Christian, C Atance, C. Neil Macrae, CJ Rathbone, CS Symons, D Berntsen, D Berntsen, D Berntsen, D Casasanto, D Cohen, D Hassabis, DC Rubin, DJ Cohen, DL Schacter, DR Addis, DR Addis, E Stephan, E Tulving, G Nigro, GR Semin, HJ Rice, Hong-jin Sun, J Glück, J Santiago, JA Robinson, JJ Skowronski, KK Szpunar, KK Szpunar, KK Szpunar, L Boroditsky, L Boroditsky, L Boroditsky, L Boroditsky, LC Trutoiu, LK Miles, LK Miles, LK Miles, LK Miles, Lynden K. Miles, M Bar, M Oliveri, M Ouellet, M Oullet, M Piefke, MA Conway, MD Henderson, MF Mason, MK Johnson, R Buehler, R Nunez, RE Núñez, RH Maki, RL Buckner, RN Preng, S Arzy, S Arzy, S Dehaene, SB Klein, SJ Maglio, T Seno, T Suddendorf, TB Rogers, V Walsh, Y Trope, Y Trope, Y Trope   +72 more
core   +3 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source