Results 41 to 50 of about 65,315 (261)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Soft Compression for Lossless Image Coding Based on Shape Recognition

Entropy, 2021
Soft compression is a lossless image compression method that is committed to eliminating coding redundancy and spatial redundancy simultaneously. To do so, it adopts shapes to encode an image.
Gangtao Xin, Pingyi Fan
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

cKd-tree: A Compact Kd-tree

IEEE Access
In the context of Big Data scenarios, the presence of extensive static datasets is not uncommon. To facilitate efficient queries on such datasets, the utilization of multiple indexes, such as the Kd-tree, becomes imperative.
Gilberto Gutierrez, Rodrigo Torres-Aviles, Monica Caniupan   +2 more
doaj   +1 more source

Spatial buildup of cochlear compression revisited

AIP Conference Proceedings
In 2013 we published an experimental study (Versteegh and Van der Heijden, doi.org/10.1007/s10162-013-0393-0) that introduced a traveling-wave perspective of cochlear nonlinearity, the so-called spatial buildup of compression and suppression. We recorded basilar membrane (BM) motion in the base of the gerbil cochlea, and obtained experimental evidence ...
Kondylidis, Kostas, Vavakou, Anna, van der Heijden, Marcel   +2 more
openaire   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Spatiotemporal cue fusion-based saliency extraction and its application in video compression

Cognitive Robotics, 2022
Extracting salient regions plays an important role in computer vision tasks, e.g., object detection, recognition and video compression. Previous saliency detection study is mostly conducted on individual frames and tends to extract saliency with spatial ...
Ke Li, Zhonghua Luo, Tong Zhang, Yinglan Ruan, Dan Zhou   +4 more
doaj   +1 more source

Inter-level Spatial Cloud Compression Algorithm

Defence Science Journal, 2014
Static images of colour clouds play an important role to predict weather conditions to schedule proof and trial activities, and deploying resources at firing locations and observation posts. In this paper, a new inter-level cloud compression architecture and algorithm has been presented.
Pranab Kumar Das Gupta, Sabyasachi Pattnaik, Manojranjan Nayak   +2 more
openaire   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source