Results 141 to 150 of about 8,118,965 (303)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Spatial Autocorrelation in a Retail Context [PDF]

open access: yes
This paper describes and applies the weighted least squares (WLS) technique that corrects for spatial autocorrelation in the residuals of hedonic regressions. Most empirical studies to date have focused on spatial autocorrelation in the housing market, i.
Charles C. Cartern, William J. Haloupek
core  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Diversified Retrieval of Spatial Data with Context.

open access: yes, 2022
The abundance and ubiquity of spatial datasets necessitates their effective and efficient retrieval. For instance, on the web, there are datasets with GIS objects or POIs (e.g. Spatialhadoop datasets), datasets with geo-tagged photographs (e.g. Flickr), online social networks (e.g. Facebook), and semantic knowledge graphs (e.g. Yago, DBpedia).
openaire   +2 more sources

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Spatial hydrological flow processes, water quality and vegetation community distributions in a natural floodplain fen

open access: yes, 2016
We studied spatial patterns in inundation water quality in a floodplain fen in Poland, resulting from interacting hydrological flow processes. Using PCA and K-means cluster analysis, we identified four clearly distinguishable water types, related to ...
Schot, P.P.   +5 more
core   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

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