Results 141 to 150 of about 509,427 (264)

Effect of aging differs for memory of object identity and object position within a spatial context. [PDF]

Learn Mem, 2021
Tran T, Tobin KE, Block SH, Puliyadi V, Gallagher M, Bakker A.   +5 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Hidden COVID-19 deaths? Exploring the Spatial context of excess death rates during the COVID-19 pandemic. [PDF]

Int J Health Geogr
Kao CL, Fotheringham AS.
europepmc   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Utilizing shallow features and spatial context for weakly supervised intracerebral hemorrhage segmentation. [PDF]

Quant Imaging Med Surg
Ma H, Tan M, Xie G, Xiong J, Xia Z, Zhang Y.   +5 more
europepmc   +1 more source

Microbial Identification, High-Resolution Microscopy and Spectrometry of the Rhizosphere in Its Native Spatial Context. [PDF]

Front Plant Sci, 2021
Bandara CD, Schmidt M, Davoudpour Y, Stryhanyuk H, Richnow HH, Musat N.   +5 more
europepmc   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

High-resolution spatial transcriptomics uncover epidermal-dermal divergences in Merkel cell carcinoma: spatial context reshapes the gene expression landscape. [PDF]

Oncogene
Lei KC, Srinivas N, Chandra M, Serobyan V, Ugurel S, Hoffmann D, Kervarrec T, Lui WO, Becker JC.   +8 more
europepmc   +1 more source

Molecular-Scale Dynamics of Long Range Retrograde Brain-Derived Neurotrophic Factor Transport Shaped by Cellular Spatial Context. [PDF]

Front Neurosci, 2022
Vermehren-Schmaedick A, Olah MJ, Ramunno-Johnson D, Lidke KA, Cohen MS, Vu TQ.   +5 more
europepmc   +1 more source