Results 181 to 190 of about 5,565,979 (320)

Preliminary Study of a Ninj1‐Loaded Bimodal Ultrasound/NIR Fluorescence Targeted Molecular Probe for Diagnosing Early‐Stage Inflammation in Coronary Microvascular Dysfunction

Advanced Healthcare Materials, EarlyView.
Coronary microvascular dysfunction (CMD) targeting remains a challenge for precise diagnosis. This work presents a dual‐modal nanoprobe (T‐IR780‐NBs) that combines ultrasound contrast with near‐infrared fluorescence. This technology utilizes proteomics‐derived antibodies that specifically localize to inflamed and injured cardiac tissue, enabling ...
Xiaohui Xu, Lina Guan, Baihetiya Tayier, Chen Yuan, Shangke Chen, Qi Shi, Yuming Mu   +6 more
wiley   +1 more source

Integrating Multi-Source Directed Gene Networks and Multi-Omics Data to Identify Cancer Driver Genes Based on Graph Neural Networks. [PDF]

Int J Mol Sci
Jiang Y, Liu Y, Qi R, Li S, Zhang T.
europepmc   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Synthesised database of wild bee and hoverfly records in Europe. [PDF]

Sci Data
Sentil A, Miličić M, Benrezkallah J, Ačanski J, Andrić A, Aubert M, Bartomeus I, Biella P, Boustani M, Carstensen LB, Bogusch P, Bot S, Brau T, Budrys E, Salazar LC, Cappellari A, Carion F, Castro S, Cavaillès S, Cerretti P, Dathe HH, De Groot M, De Tandt B, Devalez J, Devorsine R, Díaz-Calafat J, Đorđević A, Dormal A, Dufrêne E, Dussaix C, Fedorova Zaytseva LA, Fiordaliso W, Flaminio S, Földesi R, Forgeois V, Gadoum S, Garrin M, Gaspar H, Gazzea E, Geppert C, Gérard M, Geslin B, Ghisbain G, Gibernau M, Grković A, Heimburg H, Herinckx A, Demeter I, Janković Milosavljević M, Janssen K, Kasparek M, Kierat J, Kleijn D, Kuhlmann M, Lair X, Lemaire S, Lenzi L, Likov L, Litman J, Lopes SB, Loureiro J, Maarten J, Maestracci PY, Marini L, Maritano U, Mei M, Mignot M, Stojnić SM, Nedeljković Z, Ockermueller E, Ortiz-Sanchez FJ, Patiny S, Paukkunen J, Pennards G, Perrard A, Petanidou T, Popov G, Popov S, Potts SG, Prokhorov A, Pruner S, Radchenko V, Radenković S, Rasmont P, Reverté S, Ricarte A, Rojo S, Romig T, Rosa P, Ruiz C, Sagot P, Santerre R, Scheper J, Selis M, Sgolastra F, Shparyk V, Siopa C, Skendžic T, Smit J, Sommaggio D, Soon V, Ssymank A, Ståhls G, Stavrinides M, Steffan-Dewenter I, Straka J, Thulier J, Tot T, Tourbez C, van Steenis J, van Steenis W, Varnava A, Veselić S, Vesnic A, Vray S, Williams P, Wood TJ, Zimmermann D, Żmuda A, Vujić A, Michez D, de Manincor N.   +121 more
europepmc   +1 more source

Biomimetic Copper‐Doped Nano‐Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia

Advanced Healthcare Materials, EarlyView.
We developed a novel copper‐doped aluminum nano‐adjuvant (CuNA) to overcome cytarabine resistance in acute myeloid leukemia (AML). CuNA effectively sensitizes drug‐resistant AML cells to cytarabine by inducing mitochondrial dysfunction and inhibiting HMGCR/GPX4 to amplify ferroptosis.
Chao He, Lingxiao Zhang, Yue Xiong, Yu Wang, Yuqing Zeng, Dandan Su, Ran Wang, Ying Li, Hongbo Chen, Fang Cheng, Zhi Ping Xu   +10 more
wiley   +1 more source

Geospatial modelling for zoonotic disease hotspot identification within a One Health framework: a systematic review. [PDF]

One Health Outlook
Nyengere J, Mbewe W, Malalu L, Tholo H, Njala AL, Sembo T, Kumpolota SW, Mvula RL, Chisenga C, Kanyika-Mbewe C, Maluwa A, Eregno FE.   +11 more
europepmc   +1 more source

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

Advanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim, Ye‐Ji Kim, Seyoung Ryu, Daeui Park, Kyoung‐Sik Moon, Yu Bin Lee, Dong Ho Woo   +6 more
wiley   +1 more source

LnCeVar 2.0: an updated resource and web tools for genomic variations disrupting ceRNA networks from single-cell/spatial transcriptomics data. [PDF]

Nucleic Acids Res
Guo Q, Liu Q, Xin M, Li H, Li J, Dai Y, Sun R, Zhang Y, He Y, Xu B, Shan X, Gao Y, Ning S, Zhi H, Wang P.   +14 more
europepmc   +1 more source

Spatial database shared

Spatial database shared under open data ...
openaire   +1 more source

Optimizing Spatial Databases

, 2011
Anda Belciu, Stefan Olaru
semanticscholar   +1 more source