Results 131 to 140 of about 217,536 (268)
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Spatial Dependence in the Self-Response: Spatial Dependence, Modeling, and Operational Consequences
The U.S.\ Census Bureau's Low Response Score (LRS) is a central planning instrument for identifying places likely to require additional self-response outreach and nonresponse follow-up. The published LRS is intentionally interpretable: it is built from tract-level covariates using an ordinary least squares specification.
openaire +2 more sources
Symbolic Analysis Applied to the Specification of Spatial Trends and Spatial Dependence. [PDF]
Entropy (Basel), 2020 Makeienko M.
europepmc +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Analysis of COVID-19 Cases' Spatial Dependence in US Counties Reveals Health Inequalities. [PDF]
Front Public Health, 2020 Saffary T +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Parametrizing the Spatial Dependence of 1H NMR Chemical Shifts in π-Stacked Molecular Fragments. [PDF]
Int J Mol Sci, 2020 Czernek J, Brus J.
europepmc +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Reply to Zadegan et al.: Spatial dependence is real, but not every correction travels well. [PDF]
Proc Natl Acad Sci U S AKunst JR, Besta T, Obaidi M.
europepmc +1 more source