Results 41 to 50 of about 3,431,524 (310)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Ecosphere, 2019 To better understand the spatial context of population dynamics of sea otters (Enhydra lutris) in Southeast Alaska (SEAK), we investigated the spatial and temporal patterns of subsistence sea otter harvest and assessed the effect of harvest on population
Wendel W. Raymond +5 more
doaj +1 more source
Ciência e Agrotecnologia, 2005 Este trabalho foi desenvolvido em um solo aluvial na Estação Experimental da Embrapa Algodão, município de Souza, Estado da Paraíba, Brasil, com o objetivo de estudar a variabilidade espacial da densidade do solo.
Antônio Ricardo Santos de Andrade +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
EconomiesThe labour supply has historically been subject to influence from the economic cycle. On the other hand, there is a paucity of research in the Latin American region examining the impact of social factors on labour participation in diverse contexts.
Ángel Maridueña-Larrea +1 more
doaj +1 more source
Econometrics, 2015 In this study, I investigate the necessary condition for the consistency of the maximum likelihood estimator (MLE) of spatial models with a spatial moving average process in the disturbance term.
Osman Doğan
doaj +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
REDUCTION OF SAMPLE SIZE IN THE ANALYSIS OF SPATIAL VARIABILITY OF NONSTATIONARY SOIL CHEMICAL ATTRIBUTES [PDF]
Engenharia Agrícola, 2019 In the study of spatial variability of soil attributes, it is essential to define a sampling plan with adequate sample size. This study aimed to evaluate, through simulated data, the influence of parameters of the geostatistical model and sampling ...
Tamara C. Maltauro +2 more
doaj +1 more source