Results 191 to 200 of about 292,395 (311)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

Research on the Measurement and Spatial Differentiation of Livelihood Capital of Yujiale Farmers in Changdao

open access: yesHaiyang Kaifa yu guanli
Island is a special area with natural and socio-economic vulnerability, which to some extent restricts the livelihood strategy choices and development of island residents.
ZHANG Shuo, QI Fengxun, QIN Weishan
doaj  

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

GENERIC COMMODITY PROMOTION AND PRODUCT DIFFERENTIATION

open access: yes
This paper considers whether generic promotion lowers the differentiation among competing brands as claimed in the 1997 Supreme Court case (Wileman et al. v. Glickman).
Crespi, John M.
core  

Inequalities in Health: Methodological Approaches to Spatial Differentiation. [PDF]

open access: yesInt J Environ Res Public Health, 2021
Hübelová D   +6 more
europepmc   +1 more source

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