Results 101 to 110 of about 4,356,268 (297)
Ingeniare: Revista Chilena de Ingeniería, 2009 En este trabajo se presenta un procedimiento para estimar la diversidad espacial en ambientes electromagnéticos de multitrayectorias, utilizando una antena de dos elementos (combinación dipolo aro-capacitor).
J.H Caltenco +3 more
doaj
, 2016 : Aim Functional diversity is a relatively recent approach to quantify species diversity and may provide a better understanding of the linkages between biological diversity and ecosystem functioning. Understanding the relationships between mammal species
González Maya, José F. +9 more
core +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Spatial Smoothing Techniques for the Assessment of Habitat Suitability [PDF]
, 2006 Precise knowledge about factors influencing the habitat suitability of a certain species forms the basis for the implementation of effective programs to conserve biological diversity.
Müller, Jörg +2 more
core +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Walkout Protest for Diversity Center
, 2015 Organizers holding signs in a walkout protest for the Diversity CenterWalkout ...
core +2 more sources
β-diversity of deep-sea holothurians and asteroids along a bathymetric gradient (NE Atlantic) [PDF]
, 2014 Measuring and understanding patterns of ?-diversity remain major challenges in community ecology. Recently, ?-diversity has been shown to consist of 2 distinct components: (1) spatial turnover and (2) species loss leading to nestedness.
Howell, K.L. +8 more
core +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source