Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Multi-dimensional matched filter identification technique for channel equalization deployed in spatial diversity receivers [PDF]
, 2009 This paper proposes a multi-dimensional matched filtering technique for spatial diversity receivers. The coefficients of the multi-dimensional matched filter are identified by making use of an adaptive filter, the update of which doesn't require the ...
Kale, I. +3 more
core +1 more source
UCMAC: A Cooperative MAC Protocol for Underwater Wireless Sensor Networks
Sensors, 2018 This paper proposes a cooperative medium access control (MAC) protocol for underwater wireless sensor networks (UWSNs) named UCMAC, which fundamentally benefits from cooperative communication.
Hee-won Kim, Tae Ho Im, Ho-Shin Cho
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
First Edition of Diversity Center Newsletter
, 2018 First Diversity Center newsletter, sent out at the beginning of 2018Documents and ...
UW Bothell Diversity Center
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Research on design strategies for wellness towns from the perspective of spatial resilience
Journal of Asian Architecture and Building EngineeringBased on spatial resilience theory, this paper explores strategies for enhancing the design of wellness towns. With the intensification of population aging in China, the wellness industry has experienced significant development opportunities, leading to ...
Guang-Da Xu, Xiao-Xiao Tong
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Recolonisation of spawning grounds in a recovering fish stock: recent changes in North Sea herring
Scientia Marina, 2009 There is evidence that the importance of the different spawning grounds of North Sea autumn-spawning herring has changed. It has been hypothesised that as herring stocks collapse, the diversity of spawning sites also collapses.
Jörn O. Schmidt +3 more
doaj +1 more source
Using Economics to Explain Spatial Diversity in a Wheat Crop: Examples from Australia and China [PDF]
Spatial diversity indicators may serve an important function for policymakers as they seek to manage crop genetic diversity and potential externalities associated with diffusion of some types of genetically improved crops.
Hu, Ruifa +3 more
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