Results 121 to 130 of about 38,923 (287)

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

open access: yesAdvanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang   +7 more
wiley   +1 more source

Spatial division multiplexing of LED strips for optical camera communication

open access: yesOptics Express
Rolling shutter based optical camera communication (RS-OCC), a promising candidate of optical wireless communication (OWC), has the advantage of unlicensed spectrum and no electromagnetic interference. Since RS-OCC can use the built-in camera of a smartphone as a receiver, it can provide flexible, low-cost, and timely private information exchange ...
Shiwen Chen   +4 more
openaire   +2 more sources

Spatial‐Wavelength Multiplexing Error‐Controlled Photonic Analog Computing System

open access: yesAdvanced Science, EarlyView.
A novel photonic integrated circuit prototype implementing the concept of general‐purpose analog computing and demonstrate its capability in radio frequency applications. The chip features a multichannel architecture and performs fully optical analog computation with frequency‐domain parallel processing. An FPGA‐based error‐correction algorithm aims to
Tao Zhu   +15 more
wiley   +1 more source

Embedded CRISPRi Enhances Gene‐Silencing Efficiency in Drosophila

open access: yesAdvanced Science, EarlyView.
Current CRISPR interference (CRISPRi) technology in Drosophila has limited efficiency. This study introduces the emCRISPRi platform, which significantly enhances transcriptional silencing efficacy by embedding inhibitory domains within the dCas9 architecture.
Pengchong Fu   +7 more
wiley   +1 more source

Non-orthogonal optical multiplexing empowered by deep learning

open access: yesNature Communications
Orthogonality among channels is a canonical basis for optical multiplexing featured with division multiplexing, which substantially reduce the complexity of signal post-processing in demultiplexing.
Tuqiang Pan   +7 more
doaj   +1 more source

Performance Optimization of 120 Gbps–120 GHz Hybrid MDM-FSO Utilizing Non-Coherent Modified Duobinary Modulations for Optical Wireless Distributed Networks

open access: yesApplied Sciences
This study proposes optimizing the performance of free space optic signal transmission using spatial division multiplexing. The research uses different modified duobinary modulation schemes to model and optimize three hybrid mode division multiplexing ...
Rabiu I. Sabitu, Amin Malek
doaj   +1 more source

Demonstration of a spatial-division multiplexing self-healing ring network

open access: yesOptics Express
This work demonstrates a spatial-division multiplexing self-healing ring protection scheme. A 3-node, 2-fiber ring with a recirculating length of 139.3 km is implemented using 4-core weakly-coupled multicore working and protection fibers and supported by core-pumped multicore amplifiers.
Ruben S. Luis   +4 more
openaire   +2 more sources

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto   +20 more
wiley   +1 more source

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

open access: yesAdvanced Science, EarlyView.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo   +14 more
wiley   +1 more source

Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications

open access: yesAdvanced Science, EarlyView.
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun   +19 more
wiley   +1 more source

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