Results 71 to 80 of about 4,015,131 (203)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Spatial Thinking across the College Curriculum, Position Papers [PDF]

open access: yes, 2012
More than 40 position papers were prepared by participants prior to meeting in Santa Barbara. The objective was  to explore from a multi-discipline perspective the potential values and challenges of formulating curricula to advance the role of spatial ...
Spatial Intelligence Learning Center, Temple University   +1 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Domain Adaptation in Steganalysis for the Spatial Domain

open access: yesElectronic Imaging, 2018
Li Lin 0004   +4 more
openaire   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Spatial Science News from Urban Development: Industry Report August 2007 [PDF]

open access: yes, 2007
Spatial Science Contributes to Samford Ecological Research Facility; Spatial Science/Surveying undergraduate and postgraduate students have embarked on a number of projects at this unique site.
Webb, Robert M.
core  

Maritime Domain Protections Research Group (archived) [PDF]

open access: yes, 2013
The Maritime Domain Protection Research Group (formerly known as the Maritime Domain Protection Task Force) was formed to investigate issues surrounding protection of the United States, its vessels, and citizens from terrorist threats originating in the ...

core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Spatial Science News from QUT: Industry Report, Winter 2008 [PDF]

open access: yes, 2008
Spatial Sciences at SERF; Alumni Activities; GPS Measurement Survey at Coombabah ...
Webb, Robert M.
core  

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