Results 71 to 80 of about 12,348,131 (312)

Industrial agglomeration, international R&D capital and air pollution-based on provincial spatial panel data

open access: yesFrontiers in Environmental Science
Introduction: This paper presents a spatial effect model to examine the impact of industrial agglomeration and international R&D capital technology spillover on air pollution.Methods: The study utilizes spatial panel data from 30 provinces and cities
Dawei Gao, Yan Deng, Zhengyang Chen
doaj   +1 more source

Study on Longitudinal Deformation Analysis and Support Technology of Surrounding Rock in Roadway Excavation

open access: yesMeikuang Anquan, 2020
To study the influence of excavation space effect on roadway excavation, Hoek’s displacement coefficient equation is used to describe the longitudinal deformation law of roadway surrounding rock under the spatial effect, and the relationship between the
GU Shuancheng, WANG Bin, SUN Wei
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

An integrated framework to assess spatial and related implications of biomass delivery chains [PDF]

open access: yes, 2011
The overall objective of the ME4 research project was to develop an integrated framework to assess and analyse the spatial implications and related opportunities and consequences of an increased implementation of biomass delivery chains for energy ...
Sanders, J.P.M.   +3 more
core  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

The impact of agricultural technological innovation on residents’ health and its spatial effects

open access: yesFrontiers in Public Health
In response to China’s vigorous promotion of health and green, low-carbon development, agricultural technological innovation, as a crucial tool for advancing sustainable development, is essential in promoting residents’ health.
Yuan Zhao   +3 more
doaj   +1 more source

Control of spatial effects due to neighboring palms in coconut (Cocos nucifera) experiments

open access: yesCORD, 2007
The RCBD is the most robust design for field experimentations in coconut. In this study the effect of neighboring palms to control local variation in field experiments of coconut was evaluated using two long-term coconut trials.
T. S. G. Peiris
doaj   +1 more source

Spatial clustering method for geographic data [PDF]

open access: yes, 2002
In the process of visualizing quantitative spatial data, it is necessary to classify attribute values into some class divisions. In a previous paper, the author proposed a classification method for minimizing the loss of information contained in ...
Osaragi, Toshihiro
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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