Results 51 to 60 of about 318,466 (264)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Listening to the Space of Music

open access: yesRivista di Estetica, 2017
A person listening to music can be said to “hear space” in two senses: metaphorically, when the musical features of a composition, such as melody, harmony or rhythm, evoke a space (e.g., if she hears a “rising” melodic line) or suggest abstract concepts ...
Elvira Di Bona
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Beyond the Drawing: Ethnography and Architecture as Contested Narratives of the Human Experience of Dwelling

open access: yesHumans
This study interrogates the interplay between architectural practice and ethnographic inquiry to elucidate human spatial experience across time and culture.
Jose Abásolo-Llaría   +1 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Virtual Reality As A Spatial Experience For Architecture Design: A Study of Effectiveness for Architecture Students

open access: yesSHS Web of Conferences, 2018
Studios. This ability gained through visual design thinking. The spatial experience honed by three dimensional thinking from the medium diversity. The spatial experience learned through a room layout, proportion, and composition.
Sapto Pamungkas Luhur   +2 more
doaj   +1 more source

Preliminary experiments in spatial robot juggling

open access: yes, 2006
In a continuing program of research in robotic control of intermittent dynamical tasks, we have constructed a three degree of freedom robot capable of “juggling” a ball falling freely in the earth's gravitational field. This work is a direct extension of that previously reported in [7, 3, 5, 4].
Alfred A. Rizzi, Daniel E. Koditschek
openaire   +2 more sources

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Neuroarchitecture and spatial stress: a bibliometric mapping and methodological gap analysis (2000–2025)

open access: yesJournal of Asian Architecture and Building Engineering
Architectural design today is shaped not only by aesthetics and functionality but also by user perception and emotional responses. Accurately defining the relationship between environment and individual is essential for improving perceptual quality and ...
Burcu Yazıcı, Emel Birer
doaj   +1 more source

Multimodal Spatial Transcriptomics Reveals the Developing Human Liver Niche at Single-Cell Resolution

open access: yesGastro Hep Advances
Background and Aims: A comprehensive understanding of the liver niche during development provides insights into a unique, naturally occurring multifunctional multicellular environment.
Michael Bailey   +3 more
doaj   +1 more source

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