Results 1 to 10 of about 113,115 (217)
Spatial filtering in multichannel magnetoencephalography [PDF]
Journal of Biomedical Engineering, 1989 Partial differential equations in boundary-value problems have been studied in order to estimate the influence of several geometrical and physical parameters involved in the outward transmission of the brain's magnetic field. Explicit Green kernels are used to obtain integral forms of generalized solutions which can be deduced from each other, as ...
Nicolas, P., Kouwenhoven, M.
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Spatial filtering of Structured Light [PDF]
Education and Training in Optics & Photonics Conference 2021, 2020 We present an approach to filter amplitude noise from arbitrary beam profiles. This work forms a tutorial on Fourier optics by enhancing the textbook case of Gaussian beams to more interesting cases of structured light.
Pinnell, Jonathan +2 more
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Filters for Spatial Point Processes [PDF]
SIAM Journal on Control and Optimization, 2009 We study the general problem of estimating a “hidden” point process $\mathbf{X}$, given the realization of an “observed” point process $\mathbf{Y}$ (possibly defined in different spaces) with known joint distribution. We characterize the posterior distribution of $\mathbf{X}$ under marginal Poisson and Gauss-Poisson priors and when the transformation ...
Sumeetpal S. Singh +3 more
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Denoising based on spatial filtering [PDF]
Journal of Neuroscience Methods, 2008 We present a method for removing unwanted components of biological origin from neurophysiological recordings such as magnetoencephalography (MEG), electroencephalography (EEG), or multichannel electrophysiological or optical recordings. A spatial filter is designed to partition recorded activity into stimulus-related and stimulus-unrelated components ...
Alain, de Cheveigné, Jonathan Z, Simon
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source