Results 61 to 70 of about 1,099,069 (219)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

A Texture-Considerate Convolutional Neural Network Approach for Color Consistency in Remote Sensing Imagery

Remote Sensing
Remote sensing allows us to conduct large-scale scientific studies that require extensive mapping and the amalgamation of numerous images. However, owing to variations in radiation, atmospheric conditions, sensor perspectives, and land cover, significant
Xiaoyuan Qian, Cheng Su, Shirou Wang, Zeyu Xu, Xiaocan Zhang   +4 more
doaj   +1 more source

Hydrological Analysis Using Satellite Remote Sensing Big Data and CREST Model

IEEE Access, 2018
Hydrological modeling significantly contributes to the understanding of catchment water balance and water resource management and mitigates negative impacts of flooding.
Jun Ma, Weiwei Sun, Gang Yang, Dianfa Zhang   +3 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Virtual 3D City Model Generation in CityGML [PDF]

ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences
As the urban digital transformation continues to advance, virtual 3D city models have become essential tools for urban planning, traffic management, environmental assessment, and virtual reality applications.
C. Zhao, Y. Ogawa, L. Liao, Y. Sekimoto
doaj   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Vulnerability Analysis of Aquaculture to Typhoon Disasters in Island Regions: Evidence from the Zhoushan and Wenzhou Islands

Redai dili
Islands are sensitive zones of sea-land interaction and typical ecologically fragile areas that are highly vulnerable to natural disasters, especially marine aquaculture, which is sensitive and at high risk to typhoon disasters; additionally, they are ...
Wang Yu, Yuan Haihong, Shen Langzi, Liu Ye, Yang Panpan   +4 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source