Results 41 to 50 of about 10,940,549 (311)

SDI and crowdsourced spatial information management automation for disaster management

open access: yes, 2015
Modern disaster reporting is becoming increasingly sophisticated with the ready access to social media and user-friendly online mapping tools. Citizen engagement in location enabled disaster reporting is more obvious, and the availability of crowd ...
McDougall, K., Koswatte, S., Liu, X.
core   +1 more source

Uncertainty in Historical Land-Use Reconstructions with Topographic Maps

open access: yesQuaestiones Geographicae, 2014
The paper presents the outcomes of the uncertainty investigation of a long-term forest cover change analysis in the Polish Carpathians (nearly 20,000 km2) and Swiss Alps (nearly 10,000 km2) based on topographic maps. Following Leyk et al.
Kaim Dominik   +6 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Spatial variation in size at onset of maturity of female southern rock lobster Jasus edwardsii around Tasmania, Australia

open access: yesScientia Marina, 2006
P align=justify>The size at onset of maturity (SOM) of female Jasus edwardsii (Hutton, 1875) was estimated at 50 sites around Tasmania, Australia, based on the presence of ovigerous setae.
Caleb Gardner   +4 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Poznań School of Socio-Economic Geography (And Spatial Management) of Adam Mickiewicz University (In Poznań)

open access: yesQuaestiones Geographicae, 2019
This article presents the general characteristics of the Poznań school of socio-economic geography (and spatial management). Scientific school is usually understood as a community of scholars, representatives of a given scientific discipline, associated ...
Parysek Jerzy J.
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Seasonal, Annual, and Decadal Distribution of Three Rorqual Whale Species Relative to Dynamic Ocean Conditions Off Oregon, USA

open access: yesFrontiers in Marine Science, 2022
Whale populations recovering from historical whaling are particularly vulnerable to incidental mortality and disturbance caused by growing ocean industrialization.
S. Derville   +4 more
doaj   +1 more source

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