Results 81 to 90 of about 4,258,489 (302)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Challenges for identifying the neural mechanisms that support spatial navigation: the impact of spatial scale [PDF]

, 2014
Spatial navigation is a fascinating behavior that is essential for our everyday lives. It involves nearly all sensory systems, it requires numerous parallel computations, and it engages multiple memory systems.
Wolbers, Thomas, Thomas eWolbers, Wiener, J.M., Thomas Wolbers, Thomas Wolbers, Jan M. Wiener   +5 more
core   +1 more source

Characterization of spatial memory reconsolidation [PDF]

Learning & Memory, 2014
Reconsolidation is necessary for the restabilization of reactivated memory traces. However, experimental parameters have been suggested as boundary conditions for this process. Here we investigated the role of a spatial memory trace's age, strength, and update on the reconsolidation process in mice.
Bacquié, Elodie, de Jaeger, Xavier, Courtey, Julie, Brus, Maïna, Artinian, Julien, Villain, Hélène, Roullet, Pascal   +6 more
openaire   +4 more sources

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Testing Conclusions From Functional Imaging of Working Memory with Data From Acute Stroke

Behavioural Neurology, 2007
Functional imaging studies indicate that the left hemisphere mediates verbal working memory, while the right hemisphere mediates both verbal and spatial working memory.
Lisa E. Philipose, Hannah Alphs, Vivek Prabhakaran, Argye E. Hillis   +3 more
doaj   +1 more source

Spatial memory and animal movement [PDF]

Ecology Letters, 2013
AbstractMemory is critical to understanding animal movement but has proven challenging to study. Advances in animal tracking technology, theoretical movement models and cognitive sciences have facilitated research in each of these fields, but also created a need for synthetic examination of the linkages between memory and animal movement. Here, we draw
Fagan, William F., Lewis, Mark A., Auger-Méthé, Marie, Avgar, Tal, Benhamou, Simon, Breed, Greg, LaDage, Lara, Schläge, Ulrike E., Tang, Wen-wu, Papastamatiou, Yannis P., Forester, James, Mueller, Thomas   +11 more
openaire   +3 more sources

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Neural processes underpinning episodic memory [PDF]

, 2009
Episodic memory is the memory for our personal past experiences. Although numerous functional magnetic resonance imaging (fMRI) studies investigating its neural basis have revealed a consistent and distributed network of associated brain regions ...
Hassabis, D, Hassabis, D.
core  

Spatial Inferences in Narrative Comprehension: the Role of Verbal and Spatial Working Memory [PDF]

, 2016
During the comprehension of narrative texts, readers keep a mental representation of the location of protagonists and objects; a breach in spatial coherence is detected by longer online reading times (consistency effect).
Irrazabal, Natalia Carolina, Burin, Debora Ines   +1 more
core   +1 more source

The Gallery of Memories (GA-ME): A Novel Virtual Navigation Tool for the Study of Spatial Memory

Information
For the vast majority of spatial navigation research, experimental tasks are implemented in real-world environments. In recent decades, there has been an increasing trend toward virtual environments, which offer several benefits compared to their real ...
Zsolt Ternei, Zoltan Nadasdy
doaj   +1 more source